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UnknownCediranib for metastatic alveolar soft part sarcoma.
Not available
S-EPMC3677840 | biostudies-literature
UnknownRandomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597.
Not available
S-EPMC3821010 | biostudies-literature
ProteomicsCharacterization of proteome changes after 48 hours of TR-57 (ClpP agonist) treatment
ONC201 is a first-in-class, FDA approved small molecule activator of the mitochondrial ATP-dependent caseinolytic peptidase P (ClpP). This and other related small molecules referred to as ClpP agonists, exert antiproliferative effects in several cancer cell types. We report that ONC201 and highly p...
ORGANISM(S): Homo sapiens (Human) 
2026-09-21 | PXD067842 | Pride
Cell cycle arrest Mitochondrial metabolism Regulation of cell death Clpp agonist Dna damage Triple-negative breast cancer Senescence 
ProteomicsMarkers of neutrophil degranulation in the lung microenvironment linked to idiopathic pulmonary fibrosis severity and survival
Idiopathic pulmonary fibrosis (IPF) leads to progressive loss of lung function and mortality. Understanding mechanisms and markers of lung injury in IPF is paramount to improving outcomes for these patients. Despite the lack of systemic involvement in IPF, many analyses focus on identifying circulat...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-05-29 | MSV000098032 | MassIVE
UnknownAnti-vascular endothelial growth factor treatment for retinal conditions: a systematic review and meta-analysis.
Not available
S-EPMC6549720 | biostudies-literature
TranscriptomicsWhole Genome Sequencing Informs Therapeutic Selection for Pancreatic Cancer
Pancreatic cancer remains one of the most lethal of malignancies and a major health burden. We performed whole genome sequencing and CNV analysis of 100 pancreatic ductal adenocarcinomas. Chromosomal rearrangements leading to gene disruption were frequent, affecting genes known to be important in pa...
ORGANISM(S): Homo sapiens 
2015-02-27 | E-GEOD-61502 | biostudies-arrayexpress
UnknownR1507, a monoclonal antibody to the insulin-like growth factor 1 receptor, in patients with recurrent or refractory Ewing sarcoma family of tumors: results of a phase II Sarcoma Alliance for Research through Collaboration study.
Not available
S-EPMC3236654 | biostudies-literature
UnknownPercutaneous Coronary Intervention Outcomes in Patients With Prior Thoracic Radiation Therapy: A Systematic Review and Meta-Analysis.
Not available
S-EPMC9822675 | biostudies-literature
ProteomicsDiscovery of a new Cushing’s syndrome PKAc mutant that is retained within anchored type I holoenzymes
Adrenal Cushing’s syndrome is a disease of cortisol hypersecretion often caused by mutations in protein kinase A catalytic subunit (PKAc). Using a personalized medicine screening platform, we discovered a new Cushing’s driver mutation, PKAc-W196G, in ~20% of patient samples analyzed. Proximity prote...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2024-02-10 | PXD045556 | Pride
Cushing's syndrome Pka 
UnknownCytogenetic prognostication within medulloblastoma subgroups.
Not available
S-EPMC3948094 | biostudies-literature
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