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Unknown3-O-Substituted-3',4',5'-trimethoxyflavonols: Synthesis and cell-based evaluation as anti-prostate cancer agents.
Not available
S-EPMC5576577 | biostudies-literature
UnknownStructure-activity relationship and pharmacokinetic studies of 3-O-substitutedflavonols as anti-prostate cancer agents.
Not available
S-EPMC6245954 | biostudies-literature
ProteomicsThe Greatwall kinase safeguards the genome integrity by balancing the kinome activity in mitosis.
Mastl is commonly overexpressed in cancer, appearing as an alternative therapeutic anticancer target. Loss of Mastl induces multiple chromosomal mitotic errors that lead to the accumulation of micronuclei and multilobulated cells with polyploidy. Our detailed analyses display that loss of Mastl quic...
ORGANISM(S): Mus Musculus (mouse) 
2020-10-15 | PXD019297 | JPOST Repository
Unknown3-O-Alkyl-2,3-dehydrosilibinins: Two synthetic approaches and in vitro effects toward prostate cancer cells.
Not available
S-EPMC4927305 | biostudies-literature
ProteomicsuDPMs in AD+CVD - Brain ureido degenerative protein modifications are associated with neuroinflammation and proteinopathy in Alzheimer's disease with cerebrovascular disease
In this study we have profiled the temporal lobe proteome of AD+CVD subjects and age-matched controls. We have studied the occurrence of uDPMs in the particulate and soluble brain proteomes isolated and analyzed by ultracentrifugation-electrostatic repulsion hydrophilic interaction chromatography (U...
ORGANISM(S): Homo sapiens (Human) 
2017-09-11 | PXD006233 | Pride
Dpms Human brain Citrullination Carbamylation 
UnknownLiquid-liquid phase separation in supercooled water from ultrafast heating of low-density amorphous ice.
Not available
S-EPMC9883474 | biostudies-literature
UnknownDiffraction data from aerosolized Coliphage PR772 virus particles imaged with the Linac Coherent Light Source.
Not available
S-EPMC7678860 | biostudies-literature
ProteomicsAD+CVD temporal lobe proteome - Gender differences in white matter pathology and mitochondrial dysfunction in Alzheimer's disease with cerebrovascular disease
Unbiased discovery-driven quantitative proteomics was performed to profile expression changes and degenerative modifications in the temporal lobe proteome (BA21) of AD+CVD patients compared to normal age-matched controls.
ORGANISM(S): Homo sapiens (Human) 
2016-04-07 | PXD003027 | Pride
Mixed dementia Dpms Dementia Ba21 
ProteomicsAKT Inhibition Promotes Non-autonomous Cancer Cell Survival [Antibody Arrays (L-507)]
Small-molecule inhibitors of AKT signaling are being in evaluated in patients with various cancer types, but have so far proven therapeutically disappointing for reasons that remain unclear. Here, we treat cancer cells with sub-therapeutic doses of Akti-1/2, an allosteric small molecule AKT inhibito...
ORGANISM(S): Homo sapiens 
2015-12-09 | E-GEOD-71892 | biostudies-arrayexpress
ProteomicsAKT Inhibition Promotes Non-autonomous Cancer Cell Survival [Antibody Arrays (L-493)]
Small-molecule inhibitors of AKT signaling are being in evaluated in patients with various cancer types, but have so far proven therapeutically disappointing for reasons that remain unclear. Here, we treat cancer cells with sub-therapeutic doses of Akti-1/2, an allosteric small molecule AKT inhibito...
ORGANISM(S): Homo sapiens 
2015-12-09 | E-GEOD-71891 | biostudies-arrayexpress
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