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MetabolomicsA statistical analysis of the effects of urease pre-treatment on the measurement of the urinary metabolome by gas chromatography–mass spectrometry
Urease pre-treatment of urine has been utilized since the early 1960s to remove high levels of urea from samples prior to further processing and analysis by gas chromatography–mass spectrometry (GC–MS). Aside from the obvious depletion or elimination of urea, the effect, if any, of urease pre-treatm...
2014-05-21 | MTBLS71 | MetaboLights
ProteomicsQuantitative proteomic analysis of plasma in major mental disorders
Emerging high-throughput proteomic technologies have recently been considered as a powerful means of identifying substrates involved in mood disorders. We performed proteomic profiling using liquid chromatography-tandem mass spectrometry to identify dysregulated proteins in plasma samples of 44, 49,...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD028841 | Pride
Human Schizophrenia Plasma Bipolar disorder Mood depression disorder 
MetabolomicsDiel metabolomics analysis of a hot spring chlorophototrophic microbial mat leads to new hypotheses of community member metabolisms
Dynamic environmental factors such as light, nutrients, salt, and temperature continuously affect chlorophototrophic microbial mats, requiring adaptive and acclimative responses to stabilize composition and function. Quantitative metabolomics analysis can provide insights into metabolite dynamics fo...
2024-02-23 | MTBLS187 | MetaboLights
ProteomicsAnti-proteolytic regulation of KRAS by USP9X/NDRG3 in KRAS-driven cancer development
Cancers with activating mutations of KRAS show a high prevalence and poor prognosis but remain intractable, requiring innovative strategies to overcome the poor targetability of KRAS. Here, we report that KRAS expression was post-translationally up-regulated through the deubiquitination of KRAS prot...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051954 | Pride
Kras protein deubiquitination  ndrg3  usp9x  pancreatic cancer 
MetabolomicsPhototrophic biofilm assembly in microbial-mat-derived unicyanobacterial consortia: model systems for the study of autotroph-heterotroph interactions
Microbial autotroph-heterotroph interactions influence biogeochemical cycles on a global scale, but the diversity and complexity of natural systems and their intractability to in situ manipulation make it challenging to elucidate the principles governing these interactions. The study of assembling p...
2014-06-24 | MTBLS75 | MetaboLights
MetabolomicsLipid metabolites as potential diagnostic and prognostic biomarkers for acute community acquired pneumonia
Early diagnosis of acute community-acquired pneumonia (CAP) is important in patient triage and treatment decisions. To identify biomarkers that distinguish patients with CAP from non-CAP controls, we conducted an untargeted global metabolome analysis for plasma samples from142 patients with CAP (CAP...
2016-08-11 | MTBLS354 | MetaboLights
UnknownValidation of Biomarker-Based ABCD Score in Atrial Fibrillation Patients with a Non-Gender CHA2DS2-VASc Score 0-1: A Korean Multi-Center Cohort.
Not available
S-EPMC9520051 | biostudies-literature
UnknownDiscriminative biogeochemical signatures of methanotrophs in different chemosynthetic habitats at an active mud volcano in the Canadian Beaufort Sea.
Not available
S-EPMC6879587 | biostudies-literature
UnknownMetabolic Surgery for Obese Type 2 Diabetes: Korean Multicenter Cohort Study.
Not available
S-EPMC12722412 | biostudies-literature
TranscriptomicsIdentification of differentially methylated regions between placentas and maternal blood cells on chromosome 18
Comparison of DNA methylation levels of chromosome 18 between placentas and blood cells of pregnant women Extracted DNA from 5 cases of placental tissues and 5 cases of maternal blood cell was subjected to MeDIP (methylated DNA immunoprecipitation) and hybridized to Affymetrix GeneChip® Human Tiling...
ORGANISM(S): Homo sapiens 
2010-12-22 | E-GEOD-22837 | biostudies-arrayexpress
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