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ProteomicsSynphilin-1 upregulates RBL2 expression and causes a G0/G1 phase cell cycle arrest in the neurons
Synphilin-1, a major component of Lewy bodies in the brain of Parkinsons disease (PD) patients, is a cytoplasmic protein that interacts with alpha-synuclein and is suggested to have cytoprotective effects in the neuronal cells. alpha-Synuclein overexpression induced re-entry of the neuronal cells in...
ORGANISM(S): Mus <mouse, Genus> (ncbitaxon:10088) 
2022-07-20 | MSV000089926 | MassIVE
ProteomicsGmax - Seed, iBAQ (Minetal,jproteomics2017)
abundance based on iBAQ, Interaction consistency score: 9.7, Coverage: 7
ORGANISM(S): 3847 
2017-00-00 | 2413455250 | PAXDB
UnknownExperimental Applications of in situ Liver Perfusion Machinery for the Study of Liver Disease.
Not available
S-EPMC6354060 | biostudies-literature
UnknownMultifaceted Natural Language Processing Task-Based Evaluation of Bidirectional Encoder Representations From Transformers Models for Bilingual (Korean and English) Clinical Notes: Algorithm Development and Validation.
Not available
S-EPMC11539635 | biostudies-literature
ProteomicsTotal and synaptosomal proteomic analysis
Autism spectrum disorders (ASD) represent neurodevelopmental disorders characterized by social deficits, repetitive behaviors, and various comorbidities, including epilepsy. ANK2, which encodes a neuronal scaffolding protein, is frequently mutated in ASD, but its in vivo functions and disease-relate...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-03-19 | MSV000091510 | MassIVE
UnknownHigher body mass index is associated with an increased risk of multiplicity in surveillance colonoscopy within 5 years.
Not available
S-EPMC5660255 | biostudies-literature
UnknownMitochondrial Double-Stranded RNA in Exosome Promotes Interleukin-17 Production Through Toll-Like Receptor 3 in Alcohol-associated Liver Injury.
Not available
S-EPMC7297661 | biostudies-literature
UnknownGlutamate Signaling in Hepatic Stellate Cells Drives Alcoholic Steatosis.
Not available
S-EPMC6834910 | biostudies-literature
UnknownImproving dual targeting selectivity in T-cell engagers via synapse-gated and affinity-tuned trispecific antibody design.
Not available
S-EPMC12520116 | biostudies-literature
TranscriptomicsSTAT3-mediated CD133 upregulation promotes hepatocellular carcinoma
We identified a novel mechanism by which IL-6/STAT3 signaling up-regulates CD133 expression and promotes HCC progression. STAT3 activation upregulates the expression of CD133 during liver carcinogenesis. Targeting STAT3-mediated CD133 overexpression may represent a promising therapeutic strategy for...
ORGANISM(S): Homo sapiens 
2014-08-08 | E-GEOD-60194 | biostudies-arrayexpress
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