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UnknownThe detection of a strong episignature for Chung-Jansen syndrome, partially overlapping with Borjeson-Forssman-Lehmann and White-Kernohan syndromes.
Not available
S-EPMC11186873 | biostudies-literature
MetabolomicsAutomated Label-free Quantification of Metabolites from Liquid Chromatography–Mass Spectrometry Data (Simulated)

Liquid chromatography coupled to mass spectrometry (LC-MS) has become a standard technology in metabolomics. In particular, label-free quantification based on LC-MS is easily amenable to large-scale studies and thus well suited to clinical metabolomics. Large-scale studies, however, require autom...

2015-12-16 | MTBLS235 | MetaboLights
UnknownGPs' experienced challenges and strategies for supporting patient self-management in disease management programs for type 2 diabetes mellitus and coronary heart disease - a qualitative study.
Not available
S-EPMC12255095 | biostudies-literature
UnknownSARS-CoV-2 Infection or COVID-19 mRNA Vaccination Elicits Partially Different Spike-Reactive Memory B Cell Responses in Naive Individuals.
Not available
S-EPMC12474496 | biostudies-literature
ProteomicsThe natural diversity of the yeast proteome links aneuploidy tolerance to protein turnover
Accessing the natural genetic diversity of species unveils hidden genetic traits, clarifies gene functions, and allows assessment of the generalizability of laboratory findings. One notable discovery made in Saccharomyces cerevisiae natural isolates is frequent (~20%) aneuploidy – an imbalance in ch...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-03-13 | PXD048219 | Pride
Aneuploidy Protein stability Yeast Silac 
ProteomicsThe bovine cumulus proteome of cumulus oocyte complexes that successfully matured or failed to mature after maturation in-vitro and in-vivo
The oocyte forms a complex with their somatic cumulus cells within the follicle throughout the preovulatory maturation steps. Cumulus cells support their oocyte not only through mechanical protection but also with a close bidirectional exchange of metabolites. Analysis of the oocytes cumulus gives t...
ORGANISM(S): Bos taurus (Bovine) 
2020-06-30 | PXD016679 | Pride
Cumulus Proteomics Oocyte 
UnknownMetabolomics reveals effects of maternal smoking on endogenous metabolites from lipid metabolism in cord blood of newborns.
Not available
S-EPMC4783445 | biostudies-literature
UnknownAn individual participant data meta-analysis on metabolomics profiles for obesity and insulin resistance in European children.
Not available
S-EPMC6433919 | biostudies-literature
MetabolomicsNovel Potential Diagnostic Serum Biomarkers of Metabolomics in Osteoarticular Tuberculosis Patients: A Preliminary Study

Osteoarticular tuberculosis is one of the extrapulmonary tuberculosis, which is mainly caused by direct infection of Mycobacterium tuberculosis or secondary infection of tuberculosis in other parts. Due to the low specificity of the current detection method, it is leading to a high misdi...

2022-04-08 | MTBLS4187 | MetaboLights
ProteomicsRepurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms
To combat methicillin-resistant Staphylococcus aureus (MRSA) infections novel drugs addressing unprecedented and resistance-free targets are desperately needed. From a screen of human kinase inhibitors, we find that the anti-cancer drug sorafenib effectively kills MRSA strains. By dissection of the ...
ORGANISM(S): Staphylococcus aureus subsp. aureus NCTC 8325 
2022-01-19 | PXD008070 | Pride
Drug repurposing  antibacterial screening  bactericidal activity  spsb  staphylococcus aureus  mrsa  biofilm  persister  secretome  affinity-based protein profiling  chemical proteomics  photocrosslinker 
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