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ProteomicsThree types of Leishmania mexicana amastigotes: proteome comparison by quantitative proteomic analysis
Leishmania is the unicellular parasite transmitted by phlebotomine sand fly bite. It exists in two different forms; extracellular promastigotes, occurring in the gut of sand flies, and intracellular, round-shaped amastigotes residing mainly in vertebrate macrophages. As amastigotes originating from ...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD036664 | Pride
Amastigotes L. mexicana 
ProteomicsQuantitative proteomic analysis of amastigotes from Leishmania (L.) amazonensis LV79 and PH8 strains reveals molecular traits associated with the virulence phenotype
Leishmaniasis is an antropozoonosis caused by Leishmania parasites that affects around 12 million people in 98 different countries. The disease has different clinical forms, which depend mainly on the parasite genetics and on the immunologic status of the host. The promastigote form of the parasite ...
ORGANISM(S): Leishmania <subgenus> 
2017-11-16 | PXD006321 | Pride
Clustering Virulence Lesion-derived amastigotes Proteome comparison Leishmania amazonensis 
TranscriptomicsTranscription profiling of three developmental stages of Leishmania major - earlylLog, PNA- metacyclics and mouse lesion derived amastigotes
Comparison of three developmental stages (Early Log, PNA- metacyclics and Mouse lesion Derived Amastigotes) of L.major FV1.
ORGANISM(S): Leishmania major 
2009-10-15 | E-MEXP-1864 | biostudies-arrayexpress
UnknownThree types of Leishmania mexicana amastigotes: Proteome comparison by quantitative proteomic analysis.
Not available
S-EPMC9683477 | biostudies-literature
UnknownQuantitative proteomic analysis of amastigotes from Leishmania (L.) amazonensis LV79 and PH8 strains reveals molecular traits associated with the virulence phenotype.
Not available
S-EPMC5720813 | biostudies-literature
UnknownDifferential microbicidal effects of human histone proteins H2A and H2B on Leishmania promastigotes and amastigotes.
Not available
S-EPMC3067510 | biostudies-literature
ProteomicsMembrane proteome of L. amazonensis PH8 and LV79 strains
Leishmaniasis is a serious disease caused by several species of protozoa from Leishmania genus. Parasite molecules that contribute to survival in the insect and vertebrate host are named virulence factors. We have recently shown that L. amazonensis PH8 and LV79 strains have different infectivity in ...
ORGANISM(S): Leishmania amazonensis 
2022-08-10 | PXD017870 | Pride
Virulence Gp63 Leishmania amazonensis strains Membrane proteome 
TranscriptomicsExamining the genetic basis for visceral leishmaniasis disease: Comparison of distinct Leishmania donovani isolates that cause cutaneous and visceral leishmaniasis in Sri Lanka
Among the most central questions in Leishmania research is why some species remain in the skin dermis at the site of infection by the sand fly vector whereas other species migrate to visceral organs where they cause fatal visceral leishmaniasis. Although L. donovani is the species typically responsi...
ORGANISM(S): Leishmania donovani 
2013-12-31 | E-GEOD-48475 | biostudies-arrayexpress
TranscriptomicsExpression profiling reveals differential gene expression Leishmania mexicana
We examined the Leishmania mexicana transcriptome to identify differentially regulated mRNAs using high-density whole-genome oligonucleotide microarrays designed from the genome data of a closely related species, Leishmania major. Statistical analysis on array hybridization data representing 8156 pr...
ORGANISM(S): Leishmania mexicana Leishmania major 
2006-03-10 | GSE4431 | GEO
UnknownDiscovery of novel hit compounds with broad activity against visceral and cutaneous Leishmania species by comparative phenotypic screening.
Not available
S-EPMC6345745 | biostudies-literature
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