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UnknownBuilding resilience in oncology teams: Protocol for a realist evaluation of multiple cases.
Not available
S-EPMC9098052 | biostudies-literature
TranscriptomicsUBF Is An Epigenetic Factor Required For Ribosomal RNA Gene Activity And Preinitiation Complex Assembly But Not For Nucleolar Body Formation
Upstream Binding Factor (UBF) is a unique multi-HMGB-box protein first identified as a co-factor in RNA polymerase I (RPI/PolI) transcription. However, its poor DNA sequence selectivity and its ability to generate nucleosome-like nucleoprotein complexes suggest a more generalized role in chromatin s...
ORGANISM(S): Mus musculus 
2014-08-19 | E-GEOD-55450 | biostudies-arrayexpress
TranscriptomicsCooperative binding of DNA sequence non-specific HMGbox Factor Ubf and TBP-TAF complex SL1 determines RNA Polymerase I promoter recognition in vivo and its dysfunction underlies the Ubf-E210K neuroregression syndrome
Transcription of the >200 rRNA genes (rDNA) by RNA Polymerase I (RPI) determines as much as 35% of total nuclear RNA synthesis and is a major determinant of cell growth implicated in a range of hypertrophic and developmental disorders. Activation of the rDNA involves the formation of an extended nuc...
ORGANISM(S): Mus musculus 
2021-08-31 | E-MTAB-10433 | biostudies-arrayexpress
GenomicsCooperative binding of DNA sequence non-specific HMGbox Factor Ubf and TBP-TAF complex SL1 determines RNA Polymerase I promoter recognition in vivo and its dysfunction underlies the Ubf-E210K neuroregression syndrome
Transcription of the >200 rRNA genes (rDNA) by RNA Polymerase I (RPI) determines as much as 35% of total nuclear RNA synthesis and is a major determinant of cell growth implicated in a range of hypertrophic and developmental disorders. Activation of the rDNA involves the formation of an extended nuc...
ORGANISM(S): Mus musculus 
2022-02-03 | E-MTAB-11385 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human mononuclear cells from acute megakaryoblastic leukemia with and without Down syndrome
mononuclear cells were isolated on a density gradient and RNA extracted using Trizol and the Promega SV column RNA purification. Affymetrix U133A chips were hybridised using standard procedures at the core facility of Dana Farber Cancer Institute. Experiment Overall Design: This series includes samp...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-4119 | biostudies-arrayexpress
UnknownThe new missense G376V-TDP-43 variant induces late-onset distal myopathy but not amyotrophic lateral sclerosis.
Not available
S-EPMC11068115 | biostudies-literature
UnknownEffectiveness of lifestyle interventions for individuals with severe obesity and type 2 diabetes: results from the Look AHEAD trial.
Not available
S-EPMC3177753 | biostudies-literature
UnknownThe long-term effectiveness of a lifestyle intervention in severely obese individuals.
Not available
S-EPMC3574274 | biostudies-literature
UnknownDevelopment and Implementation of a Multicenter Registry for Resuscitation-Focused Transesophageal Echocardiography.
Not available
S-EPMC12643552 | biostudies-literature
UnknownFactors influencing enrollment of African Americans in the Look AHEAD trial.
Not available
S-EPMC3843916 | biostudies-literature
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