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ProteomicsThe LC-MS/MS analysis of human leukocytes in atherosclerosis related and non-related to chronic kidney disease
We performed quantitative and qualitative proteomic analysis by nanoLC-MS/MS to study the global changes in proteome of leukocytes isolated from peripheral blood of patients in various stages of chronic kidney disease and cardiovascular disease as compared to healthy controls.
ORGANISM(S): Homo sapiens (Human) 
2021-04-30 | PXD018596 | Pride
Chronic kidney disease Cardiovascular disease Leukocytes Atherosclerosis Human Lc-ms/ms 
TranscriptomicsTranscription profiling of human peripheral blood leukocytes from CHASRS particpants
Gene expression profiling was carried out on peripheral blood leukocytes from 14 healthy older adults. The primary research question is whether gene expression differs in individuals experiencing chronically high levels of social isolation (by UCLA Loneliness Scale) vs chronically low levels of soc...
ORGANISM(S): Homo sapiens 
2009-04-23 | E-GEOD-7148 | biostudies-arrayexpress
TranscriptomicsEffects of DHA-rich n-3 fatty acid supplementation on gene expression in blood mononuclear leukocytes: the OmegAD study
The hypothesis was that 6 months of dietary n-3 FA supplementation to humans affected expression of genes that might be of significance for inflammatory processes and for Alzheimer´s disease. Effects on global gene expression profiles (Affymetrix Human Focus array) in human blood mononuclear leukocy...
ORGANISM(S): Homo sapiens 
2012-05-23 | E-GEOD-29680 | biostudies-arrayexpress
TranscriptomicsWhole-transcriptome high-throughput RNA sequencing of blood leukocytes from Parkinson's disease human patients pre- and post-deep brain stimulation
The given data set is the first deep sequencing transcriptome-wide data set of human Parkinson's disease (PD) patients RNA. The data set was produced from blood leukocytes of PD patients, from the same patients following deep brain stimulation (DBS), and from matched healthy control volunteers. Post...
ORGANISM(S): Homo sapiens 
2014-07-16 | E-GEOD-42608 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human polymorphonuclear leukocytes (PMNs) from healthy individuals vs patients with X-linked chronic granulomatous disease
Polymorphonuclear leukocytes (PMNs) were obtained from healthy individuals (Healthy1, Healthy2, Healthy3, and Healthy4) or patients with X-linked chronic granulomatous disease (XCGD1, XCGD2, XCGD3, XCGD4, XCGD5, and XCGD6). The studies were performed in accordance with a protocol approved by the Ins...
ORGANISM(S): Homo sapiens 
2007-09-29 | E-GEOD-935 | biostudies-arrayexpress
Proteomicsprimary human leukocytes identifies clearance biomarkers for Staphylococcus aureus infection
Supplementary data for primary human leukocytes identifies clearance biomarkers for Staphylococcus aureus infection.
ORGANISM(S): Human Leukocytes 
2022-07-18 | MSV000089903 | MassIVE
GenomicsRhesus macaque cecal CD45+ leukocytes
Rhesus macaque cecal CD45+ leukocytes
PRJEB73798 | ENA
TranscriptomicsHuman Splice Junction Arrays of Parkinson's Patients Leukocytes mRNA Pre- and Post-Deep Brain Stimulation
Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide and the first involving motor symptoms. Deep brain stimulation (DBS) neurosurgery treatment through electrodes implanted to the subthalamic nucleus (STN) improves dramatically the debilitating motor symptoms of th...
ORGANISM(S): Homo sapiens 
2015-05-22 | E-GEOD-37591 | biostudies-arrayexpress
GenomicsLeukocytes
Leukocytes
PRJNA576499 | ENA
ProteomicsProteome analysis of lung, lung-derived leukocytes and PBMCs in a pig model for cystic fibrosis.
In Cystic Fibrosis (CF) patients, cycles of infection and inflammation lead to fatal lung damage. Here, we made use of a CF pig model to investigate proteome alterations in lung, lung-derived leukocytes and PBMCs.
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2025-02-21 | PXD055249 | Pride
Cystic fibrosis Pig model 
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