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TranscriptomicsBowel expression profiles of infants with gastrointestinal conditions
We have employed whole genome microarray expression profiling to identify genes differentially expressed in neonatal bowel tissues of different gastrointestinal conditions. Bowel tissues were collected from infants who underwent surgery treatment for necrotising enterocolitis (NEC) and spontaneous i...
ORGANISM(S): Homo sapiens 
2014-01-21 | E-GEOD-46619 | biostudies-arrayexpress
TranscriptomicsComparison of RNA-Seq and Microarray in Transcriptome Profiling During T Cell Activation
Samples in this study probe the gene expression kinetics in human CCR6+ Th17 memory T cells activated under Th17 condition. Human CCR6+ Th17 memory T cells were purified from PBMC and gene expression was studied over a time course of 3 days after activation under Th17 condition. RNA from these samp...
ORGANISM(S): Homo sapiens 
2014-03-11 | E-GEOD-48978 | biostudies-arrayexpress
TranscriptomicsPGN induced transcriptional changes in human neonatal neutrophils
We have employed whole genome microarray expression profiling to identify genes differentially expressed in cord blood purified neutrophils after a short-term exposure to peptidoglycan (PGN). PGN induced gene expressions of neonatal neutrophils were measured at 4 hours. Three biological replicates w...
ORGANISM(S): Homo sapiens 
2013-09-04 | E-GEOD-40636 | biostudies-arrayexpress
TranscriptomicsMethylation data from Down syndrome and non-Down syndrome pediatric acute lymphoblastic leukemia cases and controls
Methylation profiling can reveal patterns of hypermethlation and hypomethylation associated with distinct biologic subtypes of acute lymphoblastic leukemia (ALL). We performed methylation profiling of Down syndrome ALL cases and controls to identify unique biologic features of this ALL subgroup. Fic...
ORGANISM(S): Homo sapiens 
2011-12-01 | E-GEOD-20872 | biostudies-arrayexpress
TranscriptomicsThrombopoietin (TPO) protects against heart damage induced by doxorubicin and infarction in rat models
In order to examine the mechanism of TPO on cardiac protection against DOX damage, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to delineate the TPO cardioprotective mechanism against DOX-induced cardiomyopathy Dox and TPO...
ORGANISM(S): Rattus norvegicus 
2010-12-29 | E-GEOD-15449 | biostudies-arrayexpress
TranscriptomicsSDF-1 induced transcriptional changes in human cord blood CD34+ cells
We have employed whole genome microarray expression profiling to identify genes differentially expressed in cord blood enriched CD34+ cells(>95%) after a short-term exposure to the chemokine stromal cell-derived factor-1 (SDF-1). SDF-1 induced gene expressions of cord blood enriched CD34+ cells were...
ORGANISM(S): Homo sapiens 
2011-01-01 | E-GEOD-20891 | biostudies-arrayexpress
TranscriptomicsBowel miRNA expression profiles of infants with gastrointestinal conditions
We have employed miRNA microarray expression profiling to identify miRNA differentially expressed in neonatal bowel tissues with different gastrointestinal conditions. Bowel tissues were collected from infants who underwent surgery treatment for necrotizing enterocolitis (NEC), spontaneous intestina...
ORGANISM(S): Homo sapiens 
2015-08-24 | E-GEOD-68054 | biostudies-arrayexpress
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