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ProteomicsAtmospheric hydrogen oxidation extends to the domain archaea
Diverse aerobic bacteria use atmospheric hydrogen (H2) and carbon monoxide (CO) as energy sources to support growth and survival. Though recently discovered, trace gas oxidation is now recognised as a globally significant process that serves as the main sink in the biogeochemical H2 cycle and sustai...
ORGANISM(S): Acidianus brierleyi 
2024-02-26 | PXD040286 | Pride
Hydrogen metabolism Archaea Microbiology Archaeal physiology Trace gas oxidation Acidianus Environmental microbiology 
UnknownRapid microbial identification and colistin resistance detection via MALDI-TOF MS using a novel on-target extraction of membrane lipids.
Not available
S-EPMC7725828 | biostudies-literature
GenomicsMaintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (Dnmt3ab KO ChIP-Seq)
During mammalian development DNA methylation patterns need to be reset in primordial germ cells (PGC) and preimplantation embryos. However, many retro-transposons and imprinted genes are resistant to such global epigenetic reprogramming via hitherto undefined mechanisms. Here, we report that some of...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-47878 | biostudies-arrayexpress
GenomicsMaintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (K9 KO ChIP-Seq)
During mammalian development DNA methylation patterns need to be reset in primordial germ cells (PGC) and preimplantation embryos. However, many retro-transposons and imprinted genes are resistant to such global epigenetic reprogramming via hitherto undefined mechanisms. Here, we report that some of...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-47887 | biostudies-arrayexpress
GenomicsMaintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (Dnmt3ab KO Methyl-Seq)
During mammalian development DNA methylation patterns need to be reset in primordial germ cells (PGC) and preimplantation embryos. However, many retro-transposons and imprinted genes are resistant to such global epigenetic reprogramming via hitherto undefined mechanisms. Here, we report that some of...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-47893 | biostudies-arrayexpress
GenomicsMaintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (K9 KO 5hmC-capture-seq)
During mammalian development DNA methylation patterns need to be reset in primordial germ cells (PGC) and preimplantation embryos. However, many retro-transposons and imprinted genes are resistant to such global epigenetic reprogramming via hitherto undefined mechanisms. Here, we report that some of...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-47892 | biostudies-arrayexpress
GenomicsMaintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (K9 KO Methyl-Seq)
During mammalian development DNA methylation patterns need to be reset in primordial germ cells (PGC) and preimplantation embryos. However, many retro-transposons and imprinted genes are resistant to such global epigenetic reprogramming via hitherto undefined mechanisms. Here, we report that some of...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-47890 | biostudies-arrayexpress
TranscriptomicsMaintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (Dnmt3ab KO RNA-Seq)
During mammalian development DNA methylation patterns need to be reset in primordial germ cells (PGC) and preimplantation embryos. However, many retro-transposons and imprinted genes are resistant to such global epigenetic reprogramming via hitherto undefined mechanisms. Here, we report that some of...
ORGANISM(S): Mus musculus 
2014-06-03 | E-GEOD-47883 | biostudies-arrayexpress
UnknownTrace gas oxidation sustains energy needs of a thermophilic archaeon at suboptimal temperatures.
Not available
S-EPMC11018855 | biostudies-literature
ProteomicsTargeting G1–S Checkpoint–Compromised Cancers with Cyclin A/B RxL Inhibitors
Cancer cell proliferation requires precise control of E2F1 activity; excess activity promotes apoptosis. Here, we developed cell-permeable and bioavailable macrocycles that selectively kill small cell lung cancer (SCLC) cells with inherent high E2F1 activity by blocking RxL-mediated interactions of ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-30 | PXD055112 | Pride
Macrocycle Cyclin a E2f Cyclin b Cy/rxl motif Cdk2 Sac Synthetic lethality 
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