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ProteomicsTWIST1 methylation by SETD6 selectively antagonizes LINC-PINT expression in Glioblastoma multiforme
Glioblastoma multiforme (GBM) is the most common and aggressive malignant brain tumor among adults, which is characterized by high invasion, migration and proliferation abilities. One important process that contributes to the invasiveness of GBM is the epithelial to mesenchymal transition (EMT). EMT...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD029361 | Pride
Glioblastoma Methylation Setd6 Methyltransferase 
UnknownInhibition of cancer-associated mutant isocitrate dehydrogenases: synthesis, structure-activity relationship, and selective antitumor activity.
Not available
S-EPMC4207540 | biostudies-literature
TranscriptomicsA cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells
Dendritic cells (DC) serve a key function in host defense, linking innate detection of microbes to the activation of pathogen-specific adaptive immune responses. Whether there is cell-intrinsic recognition of HIV-1 by host innate pattern-recognition receptors and subsequent coupling to antiviral T c...
ORGANISM(S): Homo sapiens 
2010-09-09 | E-GEOD-22589 | biostudies-arrayexpress
UnknownModerate stability of risk and ambiguity attitudes across quantitative and qualitative decisions.
Not available
S-EPMC11760528 | biostudies-literature
ProteomicsMudPIT analysis of S. pombe proteins interacting with Pof8
To identify proteins interacting with Pof8, cell-free extracts of strains FP1547 harboring 3xFLAG epitope-tagged Pof8 and untagged control (FP1546) were diluted to 5 mg/ml in 8 ml of lysis buffer (50 mM Tris-HCl pH 7.5, 150 mM sodium chloride, 0.1% (v/v) NP40 and 10% (v/v) glycerol) plus complete ED...
ORGANISM(S): Schizosaccharomyces Pombe (ncbitaxon:4896) 
2021-05-24 | MSV000087493 | MassIVE
GenomicsThe maize methylome modulates mRNA splicing and reveals widespread paramutation guided by small RNA.
Methylation of chromosomal DNA in animals and plants is a fundamental mechanism of epigenetic regulation, and the maize genome, with its diverse complement of transposons and repeats, is a paradigm for transgenerational mechanisms such as paramutation and imprinting. We have determined the genome-wi...
ORGANISM(S): Zea mays 
2013-06-03 | E-GEOD-39232 | biostudies-arrayexpress
UnknownMARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome.
Not available
S-EPMC5670038 | biostudies-literature
UnknownAn open-label study evaluating the safety and efficacy of AMO-01 for the treatment of seizures in Phelan-McDermid syndrome.
Not available
S-EPMC11772936 | biostudies-literature
TranscriptomicsExpression data from multiple mouse adipose depots
Comparing gene expression profiles of murine subcutaneous vs. visceral adipose tissue. Gene expression was analyzed in two subcutaneous depots (inguinal and axillary) and two visceral depots (epididymal and mesenteric) from male C57Bl/6 mice. 4 samples were analyzed as two groups: inguinal and axill...
ORGANISM(S): Mus musculus 
2014-01-16 | E-GEOD-53307 | biostudies-arrayexpress
ProteomicsHistone protein and peptide reactivity within patients with systemic lupus erythematosus (SLE) from the ABCoN cohort
The aim of the study was to test the hypothesis that IFN high SLE patient sera is more reactive to whole histone proteins and post-translationally modified histone peptides than IFN low patient sera. We diluted patient sera 1:250 and incubated dilutions on a nitrocellulose-platform array printed wit...
ORGANISM(S): Homo sapiens 
2011-12-02 | E-GEOD-34070 | biostudies-arrayexpress
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