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MetabolomicsKidney Tissue Targeted Metabolic Profiling of Unilateral Ureteral Obstruction Rats by NMR
Renal interstitial fibrosis is a common pathological process in the progression of kidney disease. A nuclear magnetic resonance (NMR) based metabolomics approach was used to analyze the kidney tissues of renal interstitial fibrosis (RIF) rats, induced by unilateral ureteral obstruction (UUO). The co...
2017-10-09 | MTBLS361 | MetaboLights
MetabolomicsHyocholic acid species as novel biomarkers for metabolic disorders
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
MetabolomicsComparison of Two Different Astragali Radix by 1H NMR based Metabolomic Approach
Astragali Radix (AR) is a commonly used herbal drug in Traditional Chinese Medicine, and widely used for the treatment of diabetes, cardiovascular diseases, nephropathy and neuropathy. The main source of AR is the dried root of Astragalus membranaceus var. mongholicus (Bge.) Hsiao in China, and both...
2017-01-16 | MTBLS189 | MetaboLights
Proteomicsproteome in mouse brain infected by zika virus
The proteomic data of ZIKV-infected mice at 14 dpi were obtained by mass spectrometry, and we observed 68 differentially expressed proteins between infected and control mice
ORGANISM(S): Mus Musculus 
2022-07-04 | PXD035467 |
TranscriptomicsEvolution and Pathogenic Mechanism of Rice Sheath Blight Pathogen
Analysis of RNA expression of Rhizoctonia solani AG1 IA. mRNA-seq of R. solani AG1 IA at 6 timepoints during the plant infection were sequenced. Cufflinks was used for calculating expected fragments per kilobase of transcript per million fragments sequenced (FPKM) values. Expression and regulation w...
ORGANISM(S): Rhizoctonia solani AG-1 IA 
2013-01-28 | E-GEOD-32577 | biostudies-arrayexpress
UnknownA viral effector blocks the turnover of a plant NLR receptor to trigger a robust immune response
Not available
S-SCDT-10_1038-S44318-024-00174-6 | biostudies-other
MetabolomicsNMR-based metabonomics and correlative analysis reveals potential bomarkers associated with chronic atrophic gastritis
Chronic atrophic gastritis (CAG) is one of the most important pre-cancerous states with a high prevalence. Exploring of the underlying mechanism and potential biomarkers is of significant importance for CAG. In the present work, 1H NMR-based metabonomics with correlative analysis was performed to an...
2016-08-31 | MTBLS340 | MetaboLights
MetabolomicsTracer-based Metabolomics Technology to Investigate the Role and Mechanism of Fangji Huangqi Tang in Regulating Lipid Metabolism Disorders in MPC-5 Cells
Lipid metabolism disorders play a critical role in the progression of nephrotic syndrome (NS). Although the traditional Chinese medicine formula Fangji Huangqi Tang (FHT) has been shown to restore lipid homeostasis in vivo, its specific molecular targets and effects on dynamic lipid metabolism in po...
2026-09-20 | MTBLS14277 | MetaboLights
ProteomicsA Recombinant Vaccine Targeting Receptor-binding Domain of SARS-CoV-2 Spike Protein Induces Protective Immunity in Mice and Non-human Primates
The novel Coronavirus SARS-CoV-2 causes a respiratory illness called COVID-19 leading to a pandemic. An effective preventive vaccine against this virus is urgently needed.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
2020-07-30 | PXD020653 |
ProteomicsQuantitative Proteomics Analysis of CIA rats
The role of the liver is still elusive during the development of rheumatoid arthritis, although there have indeed been some reports.We used label-free quantitative proteomics to comparing the expression of proteins in the liver of normal rats and CIA rats in the different phases.
ORGANISM(S): Rattus Norvegicus 
2022-06-06 | PXD032872 |
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