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MetabolomicsNew insights into the responses of soil microorganisms to polycyclic aromatic hydrocarbon stress by combining enzyme activity and sequencing analysis with metabolomics
Polycyclic aromatic hydrocarbons (PAHs), some of the most widespread organic contaminants, are highly toxic to soil microorganisms. Whether long-term polluted soils can still respond to the fresh input of pollutants is unknown. In this study, the soil enzyme activity, soil microbial community struct...
2021-02-17 | MTBLS1196 | MetaboLights
ProteomicsIntegrative proteome and acetylome analyses of murine responses to Cryptococcus neoformans infection
Cryptococcus neoformans, an environmental opportunistic human fungal pathogen, is a causative agent for acute pulmonary infection and meningoencephalitis. Understanding the host’s response to C. neoformans infection is critical for developing effective treatment. Even though some have elucidated the...
ORGANISM(S): Mus musculus (Mouse) 
2020-04-21 | PXD016614 | Pride
Lysine acetylome Mouse lung Cryptococcus neoformans infection Mouse brain 
ProteomicsIdentification of MDN1-dependent proteome changes in Arabidopsis seeds
mdn1-1 is a weak mutant of the Arabidopsis MDN1 gene. mdn1-1 exhibits an increased seed-size phenotype. To further figure out the proteome changes in the mdn1-1 seeds, we applied the iTRAQ-based LC-MS/MS analysis. A total of 3217 proteins were identified in dry seeds of both wild type and mdn1-1. Th...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-11-12 | PXD013784 | Pride
Arabidopsis seeds Mdn1 Itraq 
UnknownMediating effects of maternal blood lipids and glucose on the relationship between pre-pregnancy body mass index and newborn birth weight in women with gestational diabetes mellitus.
Not available
S-EPMC12751765 | biostudies-literature
UnknownThe intestinal microflora diversity of aboriginal chickens in Jiangxi province, China
Not available
S-EPMC10696398 | biostudies-literature
UnknownGut microbial diversity among Yorkshire, Landrace and Duroc boars and its impact on semen quality.
Not available
S-EPMC9789229 | biostudies-literature
MetabolomicsThe gut microbiota-butyrate axis restores cardiomyocyte autophagy to alleviate Doxorubicin-induced cardiotoxicity

Abstract

Background Doxorubicin (DOX), an anthracycline chemotherapeutic agent, is widely used for treating various malignancies. However, its clinical application is limited by dose-dependent cardiotoxicity (DOX-induced cardiotoxicity, DIC). Recent studies have shown that the gut microbiot...

2025-09-16 | MTBLS12997 | MetaboLights
UnknownMicroRNA-590 Inhibits Lipoprotein Lipase Expression and Prevents Atherosclerosis in apoE Knockout Mice.
Not available
S-EPMC4580638 | biostudies-literature
MetabolomicsChanges and correlations of intestinal flora and liver metabolite profiles in mice with gallstones

There is increased appreciation for the roles of the gut-liver axis in liver and gall diseases. Specific gut microbes are associated with susceptibility to gallstone diseases,while the relationship between intestinal flora and liver metabolism in the formation of gallstones remains unclear. C57BL...

2021-08-05 | MTBLS2945 | MetaboLights
UnknownProtective immunity against mouse upper genital tract pathology correlates with high IFNγ but low IL-17 T cell and anti-secretion protein antibody responses induced by replicating chlamydial organisms in the airway.
Not available
S-EPMC3246108 | biostudies-literature
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