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ProteomicsCharacterization of protein lactylation in relation to cardiac metabolic reprogramming in neonatal mouse hearts
In mammals, the neonatal heart regenerates within a short time after birth, but adults lack this ability. We have shown that metabolic reprogramming is critical for cardiomyocyte proliferation in the neonatal heart. Herein, we revealed that cardiac metabolic reprogramming could be regulated by alter...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-02 | PXD039257 | Pride
Cell proliferation Metabolic reprogramming Postnatal heart regeneration Lactylation 
ProteomicsProteomic analyses of plasma-derived exosomes in IgG4-RD and its potential role in B cell differentiation and tissue damage
Objective: This study aimed to investigate plasma exosome profiling of IgG4-RD and its potential role in B cell differentiation and tissue damage. Methods: One hundred untreated IgG4-RD patients and 135 sex, age matched healthy controls (HCs) were enrolled in this study. A combination of liquid chro...
ORGANISM(S): Homo Sapiens 
PXD021441 |
Proteomicsthe proteomics of IGFBP6 in endothelial cells (HUVECs)
To unravel the direct mechanism of the anti-inflammatory effects of IGFBP6 in ECs, we analysed HUVECs treated with either adenovirus-Flag-IGFBP6 (Ad-IGFBP6) or control adenovirus (Ad-NC). We precipitated IGFBP6 from overexpressed ECs followed by mass spectrometry.
ORGANISM(S): Homo Sapiens 
PXD052204 |
TranscriptomicsA conserved RRM domain of B. napus FCA improves cotton fiber quality and yield by regulating cell size
Cotton fiber is actually unicellular trichome, therefor its length is really hard to be modified but very meaningful to fiber quality and yield. We have reported the function of the second RRM domain of Oryza sativa FCA in rice cell size regulation. Data shows it is highly conserved across dicotyled...
ORGANISM(S): Gossypium hirsutum 
2011-12-31 | E-GEOD-26445 | biostudies-arrayexpress
ProteomicsThe identification of VAMP8 interactive protein under normal and EBSS condition
VAMP8 was first identified as an endosomal SNARE that participates in diverse biological functions, including autophagy fusion. We investigated the protein interaction and modification of VAMP8 upon starvation condition compared with normal condition, we thus excised the GFP-VAMP8 band from the Coo...
ORGANISM(S): Homo Sapiens 
PXD064129 |
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