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TranscriptomicsSystematic evaluation of variability in simulated ChIP-chip experiments Myles_Encode
The most widely used method for detecting genome-wide protein-DNA interactions is chromatin immunoprecipitation on tiling microarrays, commonly known as ChIP-chip. Here, we conducted the first objective analysis of tiling array platforms, amplification procedures, and signal detection algorithms in ...
ORGANISM(S): Homo sapiens 
2007-12-12 | E-GEOD-9849 | biostudies-arrayexpress
GenomicsChIP seq: STAT1 and STAT3 transcription factors sense and interpret changes in inflammation through engagement of specific enhancers
Using ChIP-Seq analysis we explore regulation of gene expression changes during inflammatory peritonitis induced by challenge with bacterial ligands administered via the intra-peritoneal route. A resuspended lypholised supernatant of Staphylococcus epidermidis (SES) was administered with or without ...
ORGANISM(S): Mus musculus 
2022-04-04 | E-MTAB-10758 | biostudies-arrayexpress
TranscriptomicsChIP-chip of Drosophila Polycomb group proteins Pho and dSfmbt (PhoRC) in embryos and larvae
Analysis of binding profile of the Polycomb group proteins Pho and dSfmbt (PhoRC complex) in Drosophila melanogster at two developmental stages (embryos and larvae).
ORGANISM(S): Drosophila melanogaster 
2008-11-06 | E-TABM-525 | biostudies-arrayexpress
TranscriptomicsChIP-chip of Drosophila Polycomb group proteins Asx and Calypso (PR-DUB) in larvae
Analysis of binding profile of the Polycomb group proteins Calypso and Asx (PR-DUB) in Drosophila melanogaster larvae.
ORGANISM(S): Drosophila melanogaster 
2010-05-03 | E-TABM-908 | biostudies-arrayexpress
TranscriptomicsChIP-chip of Drosophila polycomb group protein Ph and of GlcNAc in larvae
Analysis of binding profile of the Polycomb group protein Ph and of GlcNAc sites in Drosophila melanogaster larvae.

Note some of the protocols for this experiment were changed in May 2010.
ORGANISM(S): Drosophila melanogaster 
2010-05-05 | E-TABM-697 | biostudies-arrayexpress
TranscriptomicsChIP-chip by tiling array of Drosophila Polycomb group protein Sce/Ring in larvae
Analysis of binding profile of the Polycomb group protein Sce/Ring in Drosophila melanogaster larvae.
ORGANISM(S): Drosophila melanogaster 
2011-04-03 | E-TABM-988 | biostudies-arrayexpress
TranscriptomicsPausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation: ChIP-chip data
Metazoan transcription is controlled through either coordinated recruitment of transcription machinery to the gene promoter, or subsequently, through regulated pausing of RNA polymerase II (Pol II) in early elongation. We report that a key difference between genes that use these distinct regulatory ...
ORGANISM(S): Drosophila melanogaster 
2010-10-18 | E-GEOD-20471 | biostudies-arrayexpress
TranscriptomicsCoordinated epigenetic remodelling occurs during early breast carcinogenesis [Human promoter ChIP-chip]
Dysregulation of the epigenome is a common event in malignancy. However, deciphering the earliest cancer associated epigenetic events remains a challenge. Cancer epigenome studies to date have primarily utilised cancer cell lines or clinical samples, where it is difficult to identify the initial epi...
ORGANISM(S): Homo sapiens 
2015-05-09 | E-GEOD-58880 | biostudies-arrayexpress
GenomicsTo examine the role of p300 in the SMARCA4–p53 regulatory axis, we performed ChIP-seq to assess p300, p53, H3K27ac, HDAC1, HDAC2 occupancy in BIN-67 cells
ChIP-seq was performed in BIN-67, BIN-67 p53ko, BIN-67 with SMARCA4 restoration and BIN-67 p53ko cells with SMARCA4 restoration to assess the impact of SMARCA4 and p53 on the pull downs of p300, H3K27ac, p53, HDAC1 and HDAC2.
ORGANISM(S): Homo sapiens 
2026-05-05 | E-MTAB-15700 | biostudies-arrayexpress
GenomicsEnhancer-bound LDB1 Regulates a Corticotrope Promoter Pausing Repression Program
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-02-03 | E-GEOD-64516 | biostudies-arrayexpress
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