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ProteomicsDifferential proteomics of HeLa cells treated with PDS for 24 hours and untreated HeLa cells
Pyridostatin (PDS) is a well-known G-quadruplex (G4) inducer and stabilizer, yet its target genes have remained unclear. Herein, combining mass spectrometry based proteomics strategy with bioinformatics analysis, we revealed that PDS significantly downregulated 22 proteins, of which the genes contai...
ORGANISM(S): Homo sapiens (Human) 
2022-05-19 | PXD029521 | Pride
Hela Lc-ms/ms 
ProteomicsHoneybee biology and functionality investigation of main bee products
Decipher molecular mechanism underpinning important honeybee biology such as royal jelly production using proteomics, genomics and gene editing protocols
ORGANISM(S): Apis Mellifera 
2020-06-09 | PXD019657 |
ProteomicsIdentification of the Voltage Dependent Anion Channel (VDAC1) protein implicated in the pathology of Hepatocellular carcinoma (HCC) by quantitative proteomics and integrating genetic analysis
Hepatocellular carcinoma (HCC) is a heterogeneous tumor associated with multiple signaling pathway alterations, among which mitochondrial dysfunction has been found to play an important role.
ORGANISM(S): Homo Sapiens 
2020-01-12 | PXD017072 |
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