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MetabolomicsEvidence of altered fatty acid metabolism in dogs with naturally occurring valvular heart disease and congestive heart failure

INTRODUCTION: Myxomatous mitral valve disease (MMVD) is the most common cardiac condition in adult dogs. The disease progresses over several years and affected dogs may develop congestive heart failure (HF). Research has shown that myocardial metabolism is altered in cardiac dise...

2022-03-31 | MTBLS716 | MetaboLights
ProteomicsEGR1 regulation in human bone marrow stromal cells
Human bone marrow stromal cells (BMSCs) are key elements of the hematopoietic environment and they play a central role in bone and bone marrow physiology. However, how key BMSC functions are regulated is largely unknown. We analyzed the role of the immediate early response transcription factor EGR1 ...
ORGANISM(S): Homo sapiens (Human) 
2019-06-27 | PXD011767 | Pride
Human Bone marrow Stromal cells 
TranscriptomicsTranscription profiling of human sensitive and resistant tumours identify gene expression patterns in primary breast-cancer specimens that might predict response to taxanes.
These patients proved resistant to docetaxel treatment, exhibiting residual tumor of 25% or greater remaining volume.
ORGANISM(S): Homo sapiens 
2007-10-04 | E-GEOD-349 | biostudies-arrayexpress
GenomicsNational Cancer Institute (NCI) TARGET: Therapeutically Applicable Research to Generate Effective Treatments

The Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative seeks to accelerate research in novel marker and drug development, along with understanding the molecular basis of pediatric malignancy, through identification of genomic changes associated with the follo...

phs000218.v5.p1 | EGA
UnknownA Survey of Smallholder Farms Regarding Demographics, Health Care, and Management Factors of Donkeys in Northeastern China.
Not available
S-EPMC8079733 | biostudies-literature
TranscriptomicsIntestinal myofibroblast vs skin fibroblast
Pericryptal myofibroblasts in the colon and rectum play an important role in regulating the normal colorectal stem cell niche and facilitating tumour progression. Myofibroblasts have previously mostly been distinguished from normal fibroblasts only by the expression of α smooth muscle actin (αSMA)...
ORGANISM(S): Homo sapiens 
2016-04-06 | E-GEOD-77474 | biostudies-arrayexpress
UnknownProstate-specific membrane antigen targeted protein contrast agents for molecular imaging of prostate cancer by MRI.
Not available
S-EPMC5528195 | biostudies-literature
UnknownSoluble CD14: genomewide association analysis and relationship to cardiovascular risk and mortality in older adults.
Not available
S-EPMC3826541 | biostudies-literature
ProteomicsA ubiquitin-based effector-to-inhibitor switch coordinates brain, craniofacial, and skin development
The molecular mechanisms that coordinate patterning of the embryonic ectoderm into spatially distinct lineages to form the nervous system, epidermis, and craniofacial structures are unclear. Here, biochemical disease-variant profiling reveals a posttranslational pathway that drives early ectodermal ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-14 | MSV000090711 | MassIVE
UnknownNon-invasive detection and complementary diagnosis of liver metastases via chemokine receptor 4 imaging.
Not available
S-EPMC9363530 | biostudies-literature
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