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MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
UnknownProbing Electrochemical Potential Differences over the Solid/Liquid Interface in Li-Ion Battery Model Systems.
Not available
S-EPMC8397238 | biostudies-literature
ProteomicscircITGB6-pulled down proteins in A549 cells
A549 cells were transfected with 100 pmol DNA probes complementary to the back-splice site of circITGB6 or PDPN 3’UTR region. 24 h later, cells were washed with PBS and lysed with the lysis buffer (150 mM NaCl, 20 mM Tris-HCl, pH 7.5, 1.5 mM MgCl2, 0.5% NP-40, 0.5% Triton X-100, 10% glycerol, RNase ...
ORGANISM(S): Homo sapiens (Human) 
2023-10-13 | PXD043341 | Pride
Lc-ms Proteomics Circitgb6 
ProteomicsCell-type specific labelling of glycoproteins in engineered K-562 cells (BOCTAG)
We report a strategy termed Bio-Orthogonal Cell line-specific Tagging of Glycoproteins (BOCTAG). Cells are equipped by transfection with an artificial biosynthetic pathway (mut-AGX1/NahK) that transforms an alkyne tagged sugar into the corresponding nucleotide-sugar. Only transfected cells incorpora...
ORGANISM(S): Homo sapiens (Human) 
2022-09-10 | PXD035430 | Pride
Human Mono-culture Silac Whole lysates K-562 
ProteomicsCell-type specific labelling of O-linked glycoproteins in engineered K-562 cells
We report a strategy termed Bio-Orthogonal Cell line-specific Tagging of Glycoproteins (BOCTAG). Cells are equipped by transfection with an artificial biosynthetic pathway (mut-AGX1/NahK) that transforms an alkyne tagged sugar into the corresponding nucleotide-sugar. Only transfected cells incorpora...
ORGANISM(S): Homo sapiens (Human) 
2022-09-10 | PXD035437 | Pride
Human Mono-culture Silac Whole lysates K-562 
UnknownHERV-K-specific T cells eliminate diverse HIV-1/2 and SIV primary isolates.
Not available
S-EPMC3533554 | biostudies-literature
UnknownBiexponential I = 3/2 Spin-Lattice Relaxation in the Solid State: Multiple-Quantum 7Li NMR as a Probe of Fast Ion Dynamics.
Not available
S-EPMC11000215 | biostudies-literature
GenomicsSMN and Symmetric Arginine Dimethylation of RNAP II CTD Control Termination
The C-terminal domain (CTD) of the RNA polymerase II (RNAPII) subunit POLR2A is a platform for modifications specifying the recruitment of factors that regulate transcription, mRNA processing, and chromatin remodeling. Here, we show that a CTD arginine residue (R1810 in human) that is conserved acr...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-73379 | biostudies-arrayexpress
UnknownDeciphering the phase transition-induced ultrahigh piezoresponse in (K,Na)NbO3-based piezoceramics.
Not available
S-EPMC9197837 | biostudies-literature
UnknownA pedigree-based prediction model identifies carriers of deleterious de novo mutations in families with Li-Fraumeni syndrome.
Not available
S-EPMC7462073 | biostudies-literature
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