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MetabolomicsCell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae ...
2022-03-04 | MTBLS4132 | MetaboLights
TranscriptomicsRNA-seq of coding RNA of Staphylococcus aureus COL wild type strain before and after 30 min of exposure to 176 μM neutrophil-derived oxidant hypothiocyanous acid (HOSCN) during exponential phase of an OD540 of 0.5 in LB medium
Staphylococcus aureus COL wild type strain was cultivated in LB medium in 3 biological replicates and harvested at an OD500 of 0.5 before (as control) and at 30 min after exposure to 1176 μM neutrophil-derived oxidant hypothiocyanous acid (HOSCN) stress. Cells were disrupted in 3 mM EDTA/ 200 mM NaC...
ORGANISM(S): Staphylococcus aureus 
2023-09-30 | E-MTAB-13314 | biostudies-arrayexpress
MetabolomicsSymbiotic bacteria-derived organic acids protect Delia antiqua larvae from entomopathogenic fungal infection

The protection of associated microbiota for their animal hosts against pathogen infection has been studied widely over the last 100 years. However, how those microbes protect the animal host is limitedly investigated. In former studies, body surface microbes of one insect, Delia antiqua,...

2020-11-12 | MTBLS2074 | MetaboLights
TranscriptomicsTranscriptome analysis of avian pathogenic Escherichia coli O1 in chicken serum compared to LB
Colisepticemia caused by avian pathogenic Escherichia coli (APEC) results in annual multimillion dollar losses to the poultry industry. Recent research suggests that APEC may have an important role in public health as well. Generally, colisepticemia follows a respiratory tract infection in which AP...
ORGANISM(S): Escherichia coli APEC O1 
2011-03-31 | E-GEOD-25478 | biostudies-arrayexpress
MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
UnknownEvaluation of Xpert GBS assay and Xpert GBS LB assay for detection of Streptococcus agalactiae.
Not available
S-EPMC8419907 | biostudies-literature
GenomicsTriplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation [ChIP-seq]
Children with Down syndrome (DS) have a 20-fold increased risk of developing B cell acute lymphoblastic leukemia (B-ALL). Polysomy 21 (i.e., extra copies of chr.21) is also the most frequent somatic aneuploidy among all B-ALLs. Additional B-ALLs harbor intrachromosomal amplifications of chr.21q22 (i...
ORGANISM(S): Mus musculus 
2014-04-20 | E-GEOD-48534 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human patients with diffuse large B-cell lymphoma treated with CHOP or Ritxumab-CHOP
A "Cartes d'Identite des Tumeurs" (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net). 53 samples hybridized on Affymetrix HG-U133A GeneChips arrays, for 53 patients with diffuse large B-cell lymphoma (DLBCL); patients are treated with CHOP (cyclophosphamide,...
ORGANISM(S): Homo sapiens 
2008-06-01 | E-TABM-346 | biostudies-arrayexpress
UnknownStaphylococcus sciuri Strain LCHXa is a Free-Living Lithium-Tolerant Bacterium Isolated from Salar de Atacama, Chile.
Not available
S-EPMC7285145 | biostudies-literature
ProteomicsiTRAQ dataset of Pseudomonas aeruginosa PAO1 following dially disulfide treatment
To establish the effect of DADS on the P. aeruginosa proteome, 50-mL LB medium samples were inoculated at 108 CFU/mL with exponential growth phase P. aeruginosa PAO1. DADS was then added at a concentration of 0 (control) or 0.64 mg/mL, in triplicate. The six experimental groups were incubated for 5 ...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2019-01-24 | PXD011144 | Pride
Bacteria Psuedomonas aeruginosa pao1 
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