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ProteomicsAggregated protein of heat-treated GmDnj1 mutant Orbitrap LC-MSMS
Gmdnj1-knockout mutants had diminished growth in normal conditions, and when under heat stress, exhibited more severe browning, reduced chlorophyll contents, higher reactive oxygen species (ROS) contents, and higher induction of heat stress-responsive transcription factors and ROS-scavenging enzyme-...
ORGANISM(S): Glycine max 
2021-09-09 | PXD019799 | Pride
Aggregated protein Gmdnj1 Heat stress Soybean 
ProteomicsComprehensive Identification of Soybean Long Non-coding RNAs Reveals a Subset of Small Peptide-Coding Transcripts
Long non-coding RNAs (lncRNAs) are defined as non-protein-coding transcripts that are at least 200 nucleotides long. They are known to play pivotal roles in regulating gene expression, especially during stress responses in plants. We used a large collection of in-house transcriptome data from variou...
ORGANISM(S): Glycine max 
2020-01-09 | PXD014553 | Pride
Long non-coding rna Proteomics Soybean Small peptide Transcriptomics 
TranscriptomicsGene expression profiles of hepatocyte-like cells derived from induced pluripotent stem cells (iPSCs) from donors with the Zellweger spectrum of peroxisome biogenesis disorders (PBD-ZSD) and healthy controls
Skin fibroblasts from individuals with PBD-ZSD, a rare autosomal recessive disorder caused by peroxisome assembly defects, show defects in lipid metabolism that provide the basis for clinical diagnostic tests, but are not among the cell types most affected by disease. To explore phenotypes of more c...
ORGANISM(S): Homo sapiens 
2015-05-21 | E-GEOD-69066 | biostudies-arrayexpress
MetabolomicsMass spectrometry imaging as an emerging tool for studying metabolism in human brain organoids

Human brain organoids are emerging models to study human brain development and pathology as they recapitulate the development and characteristics of major neural cell types, and enable manipulation through an in vitro system. Over the past decade, with the advent of spatial technologies,...

2023-05-23 | MTBLS7565 | MetaboLights
UnknownInteraction Between the FOXO1A-209 Genotype and Tea Drinking Is Significantly Associated with Reduced Mortality at Advanced Ages.
Not available
S-EPMC4931303 | biostudies-literature
ProteomicsProteome-Centric Cross-Omics Characterization and Integrated Network Analyses of Triple-Negative Breast Cancer
We undertook the first systemic proteomic study of a 90-case cohort of triple-negative breast cancer (TNBC) with a panoramic proteome view in quantification, phosphorylation, and DNA-binding capacity. Four integrative subtypes (iP-1-4) were stratified based on the proteome quantification profile and...
ORGANISM(S): Homo Sapiens 
2021-08-24 | PXD028102 |
TranscriptomicsTranscriptional dysregulation of synaptic genes in a human iPSC model of major mental disorders
Schizophrenia and other psychiatric disorders are postulated to be developmental disorders resulting from synapse dysfunction. How susceptibility genes for major mental disorders could lead to synaptic deficits in humans is not well-understood. Here we generated induced pluripotent stem cells (iPSCs...
ORGANISM(S): Homo sapiens 
2014-08-01 | E-GEOD-57821 | biostudies-arrayexpress
UnknownComprehensive multi-omic profiling of somatic mutations in malformations of cortical development.
Not available
S-EPMC9961399 | biostudies-literature
UnknownKidney multiome-based genetic scorecard reveals convergent coding and regulatory variants.
Not available
S-EPMC12013656 | biostudies-literature
UnknownEvaluation of individual and ensemble probabilistic forecasts of COVID-19 mortality in the United States.
Not available
S-EPMC9169655 | biostudies-literature
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