This dataset contains mass spectrometry raw files and identification results from intact N-glycoproteomic analysis of extracellular vesicles (EVs) isolated from human seminal plasma. Intact N-glycopeptides were enriched and analyzed using an Orbitrap Fusion Lumos mass spectrometer coupled to an Easy...
Nanoparticle elasticity plays crucial roles in determining nanoparticles’ physiological performances. However, the underlying mechanisms by which nanoparticle elasticity does so remain unknown.Using core-shell nanoparticles with a same PEGylated lipid bilayer shell yet cores differing in elasticity ...
This study aims to investigate the role of Streptococcus mutans–derived extracellular vesicles (SmEVs) in the progression of oral squamous cell carcinoma (OSCC). We integrated transcriptomics and DIA-based quantitative proteomics to systematically analyze changes in gene expression in CAL-27 cells a...
The incidence of non-smoking female patients with non-small cell lung cancer (NSCLC) is increasing in recent decades. However, the pathogenesis of patients is unclear and early diagnosis biomarkers are in urgent need. In this study, 136 non-smoking female subjects (65 patients with NSCLC, 6 patients...
We developed a phosphate-affinity tag-switch (PAT-switch) proteomics workflow enabling simultaneous, site-specific profiling of phosphorylation and S-nitrosylation during maize seed germination.
Skin is a thin, stratified tissue covering the entire body. It is microscopically defined by layers of epidermal epithelial cells separated from cells in the dermis by a basement membrane (BM), the skin’s extracellular matrix (ECM). The skin’s ECM binds the layers together to form the tissue’s organ...
