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no omics definedTranscription profiling by array of mouse liver from TCPOBOP treated wild type and c-jun conditional knockout animals
c-jun conditional knockout mice (c-jun?li) and relative controls (c-junf/f) were treated with TCPOBOP (3mg/Kg of body weight) and were sacrificed at 0, 1, 3 and 6 hours later. Gene expression analysis was performed on total RNA pools extracted from fresh frozen livers of 3 animals per group. For e...
ORGANISM(S): Mus musculus 
2011-03-04 | E-TABM-935 | biostudies-arrayexpress
ProteomicsLenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells
Krönke J, Udeshi ND, Narla A, Grauman P, Hurst SN, McConkey M, Svinkina T, Heckl D, Comer E, Li X, Ciarlo C, Hartman E, Munshi N, Schenone M, Schreiber SL, Carr SA, Ebert BL. Science 2014, 343, 301-305. doi:10.1126/science.1244851. Lenalidomide is a drug with clinical efficacy in multiple myeloma an...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-01-26 | MSV000079017 | MassIVE
UnknownRANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies.
Not available
S-EPMC3232218 | biostudies-literature
ProteomicsSelective killing of cancer cells by a small molecule targeting the stress response to ROS
Raj L, Ide T, Gurkar AU, Foley M, Schenone M, Li X, Tolliday NJ, Golub TR, Carr SA, Shamji AF, Stern AM, Mandinova A, Schreiber SL, Lee SW. Nature. 2011 475:231-4. doi: 10.1038/nature10167. PMCID: PMC3316487
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-01-27 | MSV000078537 | MassIVE
ProteomicsIdentification of regulators of polyploidization presents therapeutic targetsfor treatment of AMKL
Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, Moore CB, Bliss-Moreau M, Verplank L, Tolliday NJ, Mishra R, Vemula S, Shi J, Wei L, Kapur R, Lopez CK, Gerby B, Ballerini P, Pflumio F, Gilliland DG, Go...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-01-27 | MSV000078536 | MassIVE
ProteomicsHIM-17-GFP LC-MS/MS analysis in C. elegans
HIM-17 has been implicated in the regulation of DNA double-strand break (DSB) formation during meiosis in C. elegans. In a study assessing various accessory factors involved in programmed meiotic DSB formation we show data identifying protein interactions with HIM-17 obtained by assessing HIM-17-GFP...
ORGANISM(S): Caenorhabditis elegans 
2026-01-28 | PXD057629 | Pride
Him-17 C. elegans Meiosis Lc-ms/ms 
MetabolomicsMetabolic Reprogramming and Reliance in Human Skin Wound Healing
Impaired skin wound healing is a significant global health issue, especially among the elderly. Wound healing is a well-orchestrated process involving the sequential phases of inflammation, proliferation, and tissue remodeling. Although wound healing is a highly dynamic and energy-requiring process,...
2024-07-02 | MTBLS3315 | MetaboLights
TranscriptomicsSparing of muscle mass and function by passive loading in an experimental intensive care unit model
Critically ill intensive care unit (ICU) patients commonly develop severe muscle wasting and impaired muscle function, leading to delayed recovery, with subsequent increased morbidity and financial costs, and decrease quality of life of survivors. Acute Quadriplegic Myopathy (AQM) is one of the most...
ORGANISM(S): Rattus norvegicus 
2012-05-11 | E-GEOD-37944 | biostudies-arrayexpress
TranscriptomicsMicL, a new ?E-dependent sRNA, combats envelope stress by repressing synthesis of Lpp, the major outer membrane lipoprotein
In enteric bacteria, the transcription factor ?E maintains membrane homeostasis by inducing expression of proteins involved in membrane repair and of two small, regulatory RNAs (sRNAs) that downregulate synthesis of abundant membrane porins. Here, we describe the discovery of a third ?E-dependent sR...
ORGANISM(S): Escherichia coli 
2014-07-17 | E-GEOD-58637 | biostudies-arrayexpress
ModelsDuarte2007_Homo_sapiens_Metabol_Recon_1
This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public do...
2005-01-01 | MODEL6399676120 | BioModels
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