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ProteomicsIntegrated multi-omics approach reveals the role of SPEG in skeletal muscle biology including its relationship with myospryn complex
We applied multi-omics approaches (interactomic, proteomic, phosphoproteomic, and transcriptomic analyses) to assess underlying molecular pathways impacted by SPEG using mouse skeletal muscle from 2-month-old WT (n=4) and Speg-CKO (n=3) mice.
ORGANISM(S): Mus musculus (Mouse) 
2024-06-22 | PXD041692 | Pride
Lc-msms Mouse skeletal muscle 
UnknownAn explainable machine learning model predicts 30-day readmission after vertebral augmentation.
Not available
S-EPMC12774678 | biostudies-literature
ProteomicsUltradeep N-glycoproteome Atlas of Mouse Reveals Spatiotemporal Signatures of Brain Aging and Neurodegenerative Diseases
The current depth of site-specific N-glycoproteomics is insufficient to fully characterize glycosylation events in biological samples. Herein, we achieved an ultradeep and precision analysis of the N-glycoproteome of mouse tissues by integrating multiple workflows. The largest N-glycoproteomic datas...
ORGANISM(S): Mus Musculus 
2025-03-04 | PXD061436 |
ProteomicsBone-protective effects of neutralizing angiopoietin-like protein 4 monoclonal antibody in rheumatoid arthritis
Despite recent advances, rheumatoid arthritis (RA) patients remain refractory to therapy. Dysregulated overproduction of angiopoietin-like 4 protein (ANGPTL4) is thought to be contributed to the disease development. Therefore, interference with ANGPTL4 biological function may constitute a new therap...
ORGANISM(S): Rattus Norvegicus 
PXD055569 |
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