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ProteomicsA classic famous prescription alleviates inflammation in CUMS model mice via modulating MYDGF/MAP4K4/NF-κB signaling pathway, verified through UPLC-HRMS and proteomics analysis
Major depressive disorder (MDD) has caused a heavy burden on society and affected over 350 million patients worldwide currently. However, there have been 30-50% MDD patients with non-response to antidepressants. Chronic unpredictable mild stress (CUMS) has been considered as a critical trigger facto...
ORGANISM(S): Mus Sp. 
PXD053391 |
ProteomicsComparison of the significantly differentially expressed protein between K2044, K2044-8Xyl-60G, K2044-ΔXylA and K2044-ΔXylB treated with 8% xylose
The K. pneumoniae K2044, K2044-8Xyl-60G, K2044-ΔXylA and K2044-ΔXylB isolates were cultured overnight in MRS medium, then 1:200 diluted in MRS medium with 8% xylose to reach the exponential growth phase. The control group was K2044 treated with 8% xylose. The experiment was performed in triplicate.
ORGANISM(S): Klebsiella Pneumoniae 1191100241 
2024-11-04 | PXD057506 |
ProteomicsPBP inactivation and OXA treatment resulted in altered protein compositions of Staphylococcal membrane vesicles
The engineered Staphylococcus aureus strain RN4220Δagr/EDⅢ was treated with 1/4 MIC of Oxacillin (OXA), or used to construct pbp3 and pbp4 gene mutant strain. Then, the membrane vesicles (MVs) of parent strain (ΔagrMVs), OXA-treated strain (Δagr/OXAMVs), and pbp3/pbp4 mutants (Δagr/OXAMVs) were harv...
ORGANISM(S): Staphylococcus Aureus Subsp. Aureus Rn4220 
PXD057038 |
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