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1. Cellular Thermal Shift Assay (CETSA): MDA-MB-231 cells were treated for 6h with DMSO or SU212 and incubated at different temperatures and protein differences in the soluble fractions were determined. 2. Quantitative Proteomics: MDA-MB-231, MDA-MB-468, and BT549 cells were treated with DMSO (vehi...
ORGANISM(S): Homo sapiens (Human) 
2025-10-10 | PXD061466 | Pride

This project includes data derived from subjects enrolled in the BASIC3 (Baylor College of Medicine Advancing Sequencing in Childhood Cancer Care) study. BASIC3 is a National Genome Human Research Institute (NHGRI) and National Cancer Institute-funded Clinical Sequencing Exploratory Research (CSE...

Nuclear extracts were isolated from 293T cells that stably express USP44 fused with N-terminal FLAG and HA affinity tags (FH-USP44), and then analyzed by tandem affinity purification (TAP) followed by Multidimensional Protein Identification Technology (MudPIT) to uncover USP44 associated proteins. T...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 

The Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative seeks to accelerate research in novel marker and drug development, along with understanding the molecular basis of pediatric malignancy, through identification of genomic changes associated with the follo...

In this study, we used microarray analysis to investigate molecular differences underlying the determination of pigmentation in various skin types, and we used immunohistochemistry to validate the expression patterns of several interesting targets that were identified. Whole skin gene expression pro...
ORGANISM(S): Homo sapiens 
We use mRNA-seq to transcriptionally profile larval fat body and midgut tissues from Drosophila third instar larvae. These data provide insights into tissue physiology and can be used to identify tissue specific transcripts. Fat bodies from wandering third instar larvae were dissected from ~50 male ...
ORGANISM(S): Drosophila melanogaster 
Background Pediatric tuberculosis (TB) diagnosis is often challenging due to difficultly obtaining diagnostic respiratory specimens, which may contain low concentrations of Mycobacterium tuberculosis (Mtb) bacilli. However, we have reported that an immuno-affinity liquid chromatography-tandem mass s...
ORGANISM(S): Homo Sapiens 
2025-10-01 | PXD053274 | panorama
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