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TranscriptomicsENO1's RNA-binding sites in Human HeLa cells using eCLIP
eCLIP was performed for ENO1 in HeLa cells, following the protocol described by Van Nostrand et al. (2016). Libraries for six immunoprecipitation and size-matched input controls were produced. In addition, libraries were produced for two no-crosslinking controls. The libraries were sequenced using p...
ORGANISM(S): Homo sapiens 
2020-10-27 | E-MTAB-9031 | biostudies-arrayexpress
TranscriptomicsENO1 siRNA knockdown in Human HeLa cells
HeLa cells were either treated with ENO1 or control siRNAs using the protocol of the RNAiMax reagent (ENO1 pool: SMARTpool ON-TARGETplus L-004034-00-0005 and control pool: ON-TARGETplus non-targeting siRNAs 1-4). Three replicates per condition were produced.
ORGANISM(S): Homo sapiens 
2020-10-27 | E-MTAB-9032 | biostudies-arrayexpress
GenomicsENO1 siRNA knockdown in Human HeLa cells
ENO1 siRNA knockdown in Human HeLa cells
PRJEB38053 | ENA
GenomicsENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism
ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism
PRJNA761712 | ENA
ProteomicsPCNA regulates metabolism by stabilizing ENO1 and 6PGD
The essential roles of PCNA as a scaffold protein in DNA replication and repair are well established, while its more recently discovered cytosolic roles are less explored. Alpha-enolase (ENO1) and 6-phosphogluconate dehydrogenase (6PGD), important proteins in glycolysis and the Pentose Phosphate Pat...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD028314 | Pride
Glycolysis Pi3k/akt pathway Cell signaling Apim-peptide Atx-101 Apim 
GenomicsCUT-TAG of ENO1 for AML cell line
CUT-TAG of ENO1 for AML cell line
PRJNA1256343 | ENA
ProteomicsUFL1-Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression
Metabolic reprogramming toward enhanced aerobic glycolysis is a defining feature of cancer, yet how the contribution of ubiquitin-like modifications to this process remains poorly understood. Here, we identify the UFMylation E3 ligase UFL1 as a critical suppressor of glycolytic metabolism and colore...
ORGANISM(S): Homo sapiens (Human) 
2026-08-02 | PXD078510 | Pride
Ufmylation  ufl1  eno1  colorectal cancer  aerobic glycolysis 
GenomicsEffects of ENO1 knockdown and LPS+Lactate stimulation on EA.HY926 cells
Effects of ENO1 knockdown and LPS+Lactate stimulation on EA.HY926 cells
PRJNA1185214 | ENA
GenomicsENO1 couples HDAC1 to regulate histone lactylation and gene transcription
ENO1 couples HDAC1 to regulate histone lactylation and gene transcription
PRJNA1234078 | ENA
TranscriptomicsENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism
Enolase 1 (ENO1) is a glycolytic enzyme that plays essential roles in various pathological activities including cancer development. However, the mechanisms underlying ENO1-contributed tumorigenesis are not well explained. Here, we uncover that ENO1, as an RNA-binding protein, binds to the cytosine-u...
ORGANISM(S): Homo sapiens 
2023-05-19 | GSE183703 | GEO
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