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UnknownDesign of a Recyclable Photoresponsive Adsorbent via Green Synthesis of Ag Nanoparticles in Porous Aromatic Frameworks for Low-Energy Desulfurization.
Not available
S-EPMC12844071 | biostudies-literature
TranscriptomicsOsJMJ705 preferentially activates stress-responsive genes
Histone methylation is important epigenomic information for gene regulation and genome activity To evaluate genome-wide effect of OsJMJ705 on gene expression, we used the Affymetrix microarray technologies to analyze the transcriptomes of the wild type, over-expression plants and the T-DNA mutant. ...
ORGANISM(S): Oryza sativa Japonica Group 
2013-12-10 | E-GEOD-48069 | biostudies-arrayexpress
ProteomicsDiscovery of a small molecule inhibitor of the UBE2F-CRL5 axis that induces apoptosis and G2/M arrest and confers radiosensitization
Protein neddylation modification is catalyzed by a neddylation activating enzyme (NAE, E1), an E2 conjugating enzyme and an E3 ligase. In various types of human cancers, the neddylation pathway was abnormally activated. Our previous study validated that neddylation E2 UBE2F is a promising lung cance...
ORGANISM(S): Homo sapiens (Human) 
2022-10-19 | PXD036191 | Pride
Ube2f  neddylation  apoptosis  cell cycle arrest  small molecule inhibitor 
UnknownObesity promotes gastric cancer metastasis via diacylglycerol acyltransferase 2-dependent lipid droplets accumulation and redox homeostasis.
Not available
S-EPMC7276427 | biostudies-literature
ProteomicsQuantitative Proteomics Analysis with TMT Markers
Using TMT-labeled quantitative protein technique, we quantitatively analyzed the proteomes of three different resistant Bambusa pervariabilis × Dendrocalamopisis grandis under four different treatments: pathogenic fungi, pathogenic toxin, pathogenic fungi plus toxin and sterile water, and screened o...
ORGANISM(S): Bambusa Pervariabilis Bambusa Grandis 
2019-06-24 | PXD014363 |
ProteomicsMembrane proteomic analysis reveals the intestinal development is deteriorated by intra-uterine growth restriction in piglets
The alterations of the intestinal proteome was observed in intrauterine growth restriction (IUGR) piglets during early life by gel-based approaches. Nevertheless, how IUGR affects the intestinal membrane proteome during neonatal development remains unclear. Here, we applied the iTRAQ-based proteomic...
ORGANISM(S): Sus Scrofa Domesticus 
2019-03-29 | PXD013315 |
ProteomicsOocyte-specific knockout of eIF2 subunits causes apoptosis of mouse oocytes within the early growing follicles via mitochondrial dysfunctions and DNA damage
For proteomic analysis, total protein was extracted from 3000 oocytes of each genotype and then analyzed by PTM-biolab (China).
ORGANISM(S): Mus Musculus 
2024-08-01 | PXD054478 |
ProteomicscTAGE5/MEA6 regulates LBR transport to maintain nuclear envelope integrity and safeguard against aging
IP-MS of fused MEA6-GFP and the control sample were performed. For MS analyses, peptides were resuspended in 0.1% FA and analyzed by LTQ Orbitrap Elite mass spectrometer (ThermoFisher Scientific) coupled online to an Easy-nLC 1000 (Thermo Fisher Scientific) in the data-dependent mode.
ORGANISM(S): Homo Sapiens 
2025-04-24 | PXD063263 |
MetabolomicsVGLL4 modulates Paneth cells and sustains intestinal homeostasis.
Paneth cells are defensive cells in the intestinal tract, which secrete niche factors and antimicrobial peptides (AMPs) to maintain the small intestinal stem cell niche and immune homeostasis. Here, we show that Vestigial-like family member 4 (VGLL4) plays a pivotal role in maintaining small intesti...
2026-03-12 | MTBLS10456 | MetaboLights
ProteomicsDifferential proteomic and phosphoproteomic analysis of Hnrnpk conditional knockout mouse testes
In this research, we have used a global analysis of TMT-based quantitative proteome coupled with phosphopeptide-enrichment strategies to reveal the mouse testes proteome and find the PTMs associated with the RNA binding protein hnRNPK using Hnrnpk conditional knockout mouse and WT mouse testes.
ORGANISM(S): Mus Musculus 
2024-09-14 | PXD056125 |
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