Sort   by:  
 Page size 
GenomicsSMN and Symmetric Arginine Dimethylation of RNAP II CTD Control Termination
The C-terminal domain (CTD) of the RNA polymerase II (RNAPII) subunit POLR2A is a platform for modifications specifying the recruitment of factors that regulate transcription, mRNA processing, and chromatin remodeling. Here, we show that a CTD arginine residue (R1810 in human) that is conserved acr...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-73379 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human bronchial epithelial cells treated with vehicle (control), VOSO4 (V, 50 uM) or ZnSO4 (Zn, 50 uM) for 4 hours.
Human bronchial epithelial cells were treated with vehicle (control), VOSO4 (V, 50 uM) or ZnSO4 (Zn, 50 uM) for 4 hours.
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-2111 | biostudies-arrayexpress
ProteomicsSecretome from TXNIP knockout human colorectal cell line (DLD1)
Chemotherapy, the standard of care treatment for cancer patients with advanced disease, has been increasingly recognised to activate host immune responses to produce durable outcomes. Here, in colorectal adenocarcinoma (CRC) we identify oxaliplatin-induced Thioredoxin Interacting Protein (TXNIP), a ...
ORGANISM(S): Homo sapiens (Human) 
2024-08-12 | PXD051666 | Pride
Human Txnip Colorectal Secreted 
UnknownPhylogenetic association analysis with conditional rank correlation.
Not available
S-EPMC11373757 | biostudies-literature
ProteomicsSensitive detection of HIV-1 and Mycobacterium tuberculosis peptides in blood for rapid diagnosis of co-infected individuals by immuno-affinity liquid chromatography tandem mass spectrometry
We describe a blood-based immuno-affinity liquid chromatography tandem mass spectrometry (ILM) assay that quantifies proteotypic peptides derived from the Mtb virulence factor CFP10 and the HIV-1 capsid protein p24 to simultaneously diagnose HIV-1 infection and TB disease and to monitor their real-t...
ORGANISM(S): Homo Sapiens 
2023-11-15 | PXD043191 | panorama
MetabolomicsCadmium acute exposure induces metabolic and transcriptomic perturbations in human mature adipocytes
Obesity is considered as a major public health concern with strong economic and social burdens. Exposure to pollutants such as heavy metals can contribute to the development of obesity and its associated metabolic disorders, including type 2 diabetes and cardiovascular diseases. Adipose tissue is an...
2023-06-29 | MTBLS4128 | MetaboLights
MetabolomicsImpacts of the Callipyge mutation on ovine plasma metabolites
The ovine Callipyge mutation causes postnatal muscle hypertrophy localized to the pelvic limbs and torso, as well as body leanness. The mechanism underpinning enhanced muscle mass is unclear, as is the systemic impact of the mutation. To investigate potential systemic effects of the mutation, 1H NMR...
2015-01-31 | MTBLS77 | MetaboLights
UnknownEnhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation.
Not available
S-EPMC6252285 | biostudies-literature
UnknownAn "Unlikely" Pair: The Antimicrobial Synergy of Polymyxin B in Combination with the Cystic Fibrosis Transmembrane Conductance Regulator Drugs KALYDECO and ORKAMBI.
Not available
S-EPMC5300747 | biostudies-literature
MetabolomicsGenome-scale metabolic modelling of responses to polymyxins in Pseudomonas aeruginosa
Background: Pseudomonas aeruginosa often causes multidrug-resistant infections in immunocompromised patients and polymyxins are often used as the last-line therapy. Alarmingly, resistance to polymyxins has been increasingly reported worldwide recently. To rescue this last-resort class of antibiotics...
2018-02-28 | MTBLS630 | MetaboLights
Sort   by:  
 Page size