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Txnip deficient mice with hepatocellular carcinoma
ORGANISM(S): Mus musculus 
Chemotherapy, the standard of care treatment for cancer patients with advanced disease, has been increasingly recognised to activate host immune responses to produce durable outcomes. Here, in colorectal adenocarcinoma (CRC) we identify oxaliplatin-induced Thioredoxin Interacting Protein (TXNIP), a ...
ORGANISM(S): Homo sapiens (Human) 
2024-08-12 | PXD051666 | Pride
TXNIP loss expands Myc transcriptome
Txnip C247S Mouse Heart Analysis
TXNIP loss expands Myc transcriptome [RNA-seq]
TXNIP loss increases Myc genomic occupancy [ChIP-seq]
TXNIP loss
Wildtype (wt) mouse cone transcriptome change with Txnip treatment
Entry and exit from cellular quiescence require dynamic adjustments in nutrient acquisition, yet the mechanisms by which quiescent cells downregulate amino acid (AA) transport remain poorly understood. Here we show that cells entering quiescence selectively target plasma membrane-resident AA transpo...
ORGANISM(S): Homo sapiens (Human) 
2025-12-08 | PXD066527 | Pride
TXNIP loss does not increase chromatin accessibility for Myc binding.
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