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UnknownmiR-106b-25/miR-17-92 clusters: polycistrons with oncogenic roles in hepatocellular carcinoma.
Not available
S-EPMC4033436 | biostudies-literature
ProteomicsProteomics of human hippocampus
ECM proteins were up-regulated mostly in AD patients
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD072140 | Pride
Brain Hippocampus Alzheimer's disease Human 
Proteomics5×FAD mouse hippocampus ECM proteomics
ECM proteins were up-regulated mostly in both SDS-soluble and SDS-insoluble group of 5×FAD model
ORGANISM(S): Mus musculus (Mouse) 
2026-09-14 | PXD072193 | Pride
Mouse Hippocampus Alzheimer's disease 
ProteomicsLC-MS/MS identification of XPO7-interacting proteins
Identification XPO7-interating proteins by ectopically expressed FLAG-tagged XPO7 proteins in HEK293T cells and performed coimmunoprecipitation (co-IP) with FLAG antibody followed by mass spectrometry analysis.
ORGANISM(S): Homo Sapiens 
2022-11-03 | PXD037890 |
ProteomicsThe proteomic navigator of human aging
Proteins are the cornerstone of human life, yet the proteomic landscape of aging across human tissues remains largely unexplored. Here, we present a comprehensive proteomic analysis of 520 samples from 15 human tissues, spanning a 50-year lifespan. Our study compiles a proteomic encyclopedia of mult...
ORGANISM(S): Homo Sapiens 
2024-12-06 | PXD058638 |
GenomicsA Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging
Our data throw light upon the effect of WRN deficiency on gene expression and epigenomic modification, which indicates aging-associated changes from both genomic and epigenomic level. It was compared between WRN+/+ and WRN-/- in hESCs and hMSCs that the gene expression landscapes and epigenetic modi...
ORGANISM(S): Homo sapiens 
2015-05-13 | E-GEOD-52285 | biostudies-arrayexpress
MetabolomicsLipidomics profiling reveals the role of glycerophospholipid metabolism in psoriasis
Psoriasis is a common and chronic inflammatory skin disease complicated by genetic-environmental interactions. Although genomic, transcriptomic and proteomic analyses have been performed to investigate the pathogenesis of psoriasis, the role of metabolites in psoriasis, particularly of lipids, remai...
2017-08-22 | MTBLS408 | MetaboLights
ProteomicsNoninvasive urinary protein signatures combined clinical information associated with Microvascular Invasion Risk in patients with HCC
Microvascular invasion (MVI) is the main factor affecting the prognosis of patients with hepatocellular carcinoma (HCC). There is an urgent need for reliable preoperative prediction of MVI indicators in order to formulate a reasonable treatment plan for patients.
ORGANISM(S): Homo Sapiens 
2022-10-13 | PXD037409 |
ProteomicsAutophagy and biotransformation affect sorafenib resistance in hepatocellular carcinoma
As a first-line drug for treating advanced hepatocellular carcinoma, the resistance to sorafenib has always attracted attention. However, most attention has been focused on a series of mechanisms related to drug resistance caused after sorafenib treatment. In this study, we used proteomic techniques...
ORGANISM(S): Homo Sapiens 
2023-02-24 | PXD040371 |
ProteomicsOverexpress S-protein tagged mouse TBK1 protein and identify the TBK1-interacting proteins by mass spectrometry
HEK293T cells were transfected with SFB-tagged mTBK1 or an empty vector for 24 h, the cells were lysed with lysis buffer (20 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5% Triton X-100, 10% glycerol, 1 mM ethylenediaminetetraacetic acid) containing a complete protease inhibitor cocktail, followed by centrif...
ORGANISM(S): Homo Sapiens Mus Musculus 
2023-10-27 | PXD045961 |
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