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TranscriptomicsTranscription profiling of mouse germline during spermatogenesis reveals X and Y occupy a novel compartment in the post-meiotic spermatid and adopt a non-Rabl configuration
In mammals, the X and Y chromosomes are subject to meiotic sex chromosome inactivation (MSCI) during prophase I in the male germline, but their status thereafter is currently unclear. An abundance of X-linked spermatogenesis genes has spawned the view that the X must be active [1-8]. On the other ha...
ORGANISM(S): Mus musculus 
2007-12-07 | E-GEOD-4193 | biostudies-arrayexpress
UnknownRAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes.
Not available
S-EPMC8754306 | biostudies-literature
UnknownOrigin and chromatin remodeling of young X/Y sex chromosomes in catfish with sexual plasticity.
Not available
S-EPMC9945428 | biostudies-literature
Transcriptomics46,XY sex reversed females with complete androgen insensitivity syndrome
This gene set contains skin fibroblasts from either labia majora of 46,XY sex reversed females having complete androgen insensitivity syndrome due to inactivation mutations of the androgen receptor gene and from the scrotum of normal males. Both, labia majora and scrotum origin from the same embryol...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-6797 | biostudies-arrayexpress
UnknownSpeedy A governs non-homologous XY chromosome desynapsis as a unique prerequisite for XY loop-axis organization.
Not available
S-EPMC12488978 | biostudies-literature
UnknownA novel SRY pathogenic variant from a 46,XY female harboring a nonsense point mutation (G to A) in position 293.
Not available
S-EPMC8385684 | biostudies-literature
TranscriptomicsFibroblasts from genital and extragenital regions of 46,XY individuals
This dataset contains fibroblasts from different genital and extragenital regions, mostly from 46,XY individuals. Due to proven androgen receptor gene mutations, several individuals have varying degrees of undervirilization of the external genitalia ranging from complete androgen insensitivity syndr...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-6796 | biostudies-arrayexpress
TranscriptomicsGenital fibroblasts of normal males and 46,XY females with androgen insensitivity syndrome
This SuperSeries is composed of the following subset Series: GSE3871: Effects of androgen treatment on genital fibroblasts GSE3872: Baseline gene transcription in genital fibroblasts Abstract: BACKGROUND: Androgen insensitivity syndrome (AIS) comprises a range of phenotypes from male infertility to...
ORGANISM(S): Homo sapiens 
2006-03-06 | E-GEOD-4353 | biostudies-arrayexpress
UnknownSpeedy A governs non-homologous XY chromosome desynapsis as a unique prerequisite for XY loop-axis organization
Not available
S-SCDT-10_1038-S44318-025-00528-8 | biostudies-other
UnknownS100PBP interacts with nucleoporin TPR and facilitates XY crossover formation in mice.
Not available
S-EPMC12069632 | biostudies-literature
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