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ProteomicsPBRM1-deficient PBAF complexes target de novo genomic loci to activate pro-survival genes in clear cell renal cell carcinoma (BRG1 dataset)
PBRM1 is lost in 40% of clear cell renal cell carcinomas (ccRCC) and the combined loss of VHL and PBRM1 drives ccRCC tumorigenesis. PBRM1 is an accessory subunit of the PBAF subclass of the SWI/SNF chromatin remodeler and despite its well-established role as a tumor suppressor, we have limited under...
ORGANISM(S): Homo Sapiens (human) 
2021-07-24 | PXD020553 | JPOST Repository
UnknownEfficacy of ultra-short course chemotherapy for new smear positive drug susceptible pulmonary tuberculosis: study protocol of a multicenter randomized controlled clinical trial.
Not available
S-EPMC5474865 | biostudies-literature
ProteomicsIn-situ proximity labeling of proteins associated with specific circRNA and RNA G-quadruplex
We developed a method named TAPRIP (TurboID-Assisted Proximity labeling of targeted RNA Interacting Proteins.
ORGANISM(S): Homo Sapiens 
2025-01-27 | PXD060240 |
ProteomicsPBRM1-deficient PBAF complexes target de novo genomic loci to activate pro-survival genes in clear cell renal cell carcinoma (PBRM1 dataset)
PBRM1 is lost in 40% of clear cell renal cell carcinomas (ccRCC) and the combined loss of VHL and PBRM1 drives ccRCC tumorigenesis. PBRM1 is an accessory subunit of the PBAF subclass of the SWI/SNF chromatin remodeler and despite its well-established role as a tumor suppressor, we have limited under...
ORGANISM(S): Homo Sapiens (human) 
2021-07-24 | PXD020554 | JPOST Repository
ProteomicsDIA-PRM Proteomic Study of Tissue Samples Reveals Modulated Pathways and Biomarkers Related to Pelvic Organ Prolapse
To discover potential biomarker(s) for POP diagnosis and explore the molecular mechanism underlying the disease, we here applied an untargeted data-independent acquisition (DIA)-based proteomics approach on vaginal wall tissue samples from patients with POP (n = 19) and controls (n = 8).
ORGANISM(S): Homo Sapiens 
PXD042491 |
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