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TranscriptomicsDefault DNA Methylation is Preceded by Broad, Low-Level Transcription in Fetal Male Germ Cells and Is Inversely Patterned by Dynamic H3K4 Methylation (ChIP-chip and MIRA-chip)
To understand what dictates the emerging patterns of de novo DNA methylation, we mapped DNA methylation, chromatin, and transcription changes in purified fetal mouse germ cells using MIRA-chip, ChIP-chip, and strand-specific RNA-seq, respectively. De novo methylation occurred without any apparent tr...
ORGANISM(S): Mus musculus 
2013-07-31 | E-GEOD-45836 | biostudies-arrayexpress
TranscriptomicsGenomic mapping of 5-hydroxymethylcytosine in the human brain
Methylation at the 5-position of cytosine is a well-studied epigenetic pathway. In addition to 5-methylcytosine (5mC), substantial amounts of 5-hydroxymethylcytosine (5hmC) also referred to as the 6th DNA base, have been detected in certain tissues, most notably the brain. However, the genomic distr...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-27051 | biostudies-arrayexpress
Transcriptomicstomato salt response
Wild halophytic tomato has long been considered as an ideal gene donor for improving salt tolerance in tomato cultivars. Here, a wild tomato genotype, Solanum pimpinellifolium M-bM-^@M-^XPI365967M-bM-^@M-^Y is significantly more salt-tolerant than a cultivar, Solanum lycopersicom M-bM-^@M-^Xmoneymak...
ORGANISM(S): Solanum lycopersicum 
2010-05-31 | E-GEOD-16401 | biostudies-arrayexpress
UnknownGenetic mapping and identification of Rht8-B1 that regulates plant height in wheat.
Not available
S-EPMC10286341 | biostudies-literature
UnknownOptimal Thromboprophylaxis in Elderly Chinese Patients with Atrial Fibrillation (ChiOTEAF) registry: protocol for a prospective, observational nationwide cohort study.
Not available
S-EPMC5942423 | biostudies-literature
ProteomicsMass spectrometry-based protein interactome and phosphoproteomics data upon NRDE2 overexpression
The HEK293T cells transiently expressing Flag-tagged empty vector or Flag-NRDE2-WT were lysed in NETN buffer (10 mM Tris-HCl [pH 8.0], 100 mM NaCl, 1 mM EDTA, and 0.5% NP-40) and immunoprecipitated with anti-Flag M2 agarose (M8823; Sigma-Aldrich, MO, USA). After washing four times with the high stri...
ORGANISM(S): Homo Sapiens 
2024-03-31 | PXD051117 |
ProteomicsProteomic analysis of zearalenone exposure on uterine development in weaned gilts
Proteomics was used to analyze the effect of ZEA exposure on uterine development of weaned gilts
ORGANISM(S): Sus Scrofa Domesticus 
PXD036461 |
UnknownPatterns of comorbidities, clinical course, and impact of the ABC Pathway for Integrated Care in patients with atrial fibrillation: a report from the prospective Optimal Thromboprophylaxis in Elderly Chinese Patients with Atrial Fibrillation (ChiOTEAF) Registry.
Not available
S-EPMC12587286 | biostudies-literature
ProteomicsQuantitative proteomic analysis of zearalenone-induced jejunum damage in weaned piglets
A total of 16 healthy Duroc × Landrace × Yorkshire weaned piglets (35 d of age) with an average body weight (BW) of 12.39 ± 0.24 kg were randomly allotted to two treatments with 8 piglets per treatment. The weaned piglets in the control group were fed the basal diet, and the ZEA3.0 treatment was the...
ORGANISM(S): Sus Scrofa Domesticus 
PXD036686 |
ProteomicsMaternal immune activation perturbs intestinal niche through microbial glycerophospholipids and drives offspring behavioral abnormalities
Using a mouse MIA model induced by prenatal exposure to Toxoplasma gondii soluble tachyzoite antigen (STAg), we reveal that maternal gut dysbiosis, characterized by increased Firmicutes and Actinobacteria, drives offspring behavioral deficits. This dysbiosis disrupts intestinal barrier integrity and...
ORGANISM(S): Mus Musculus 
2026-03-04 | PXD075246 |
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