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Acetylated proteome data of young human dermal fibroblasts (HDFs) [Young], old HDFs [Old], FTO-knockdown HDFs [shFTO], KAT8-overexpression HDFs [KAT8] and KAT8-overexpressed HDFs after FTO deprivation [shFTO_KAT8] were analysed by LC‒MS/MS.
ORGANISM(S): Homo Sapiens 
2024-12-20 | PXD059135 |
Lentivirus expressing shRNA targeting Fto was intradermally injected into the back skin of wild-type C57BL/6j mice to locally knock down the expression of FTO in the skin. the proteome of control skin [shNC], Fto-depleted skin [shFto] were analysed by LC‒MS/MS.
ORGANISM(S): Mus Musculus 
2024-12-20 | PXD059134 |
ZIKV-infection during pregnancy can cause microcephaly in newborns, yet the underlying mechanisms remain largely unexplored. Here, we reveal extensive and large-scale metabolic reprogramming events in ZIKV-infected mouse brains. We perform a multi-omics study comprising transcriptomics, proteomics, ...
ORGANISM(S): Mus Musculus 
2021-06-18 | PXD026814 |
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