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ProteomicsA Quantitative Proteome Map of the Human Body
In this study, we quantified the relative protein levels from 12,627 genes across 32 normal human tissue types prepared by the GTEx project. Known and new tissue specific or enriched proteins were identified and compared to transcriptome data. Many ubiquitous transcripts are found to encode highly t...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-10-30 | MSV000086387 | MassIVE
ProteomicsMyeloid cell-expressed MNDA enhances M2 polarization to facilitate the metastasis of hepatocellular carcinoma
Proteomic data of exosomes induced into M2 macrophage-derived cells after THP-1 knockdown of MNDA
ORGANISM(S): Homo Sapiens 
2024-03-20 | PXD050839 |
ProteomicsTargeted protein degradation reveals Pol II heterogeneity and functional diversity
RNA polymerase II (Pol II) subunits are thought to be involved in various transcription-associated processes, but it is unclear whether they play different regulatory roles in modulating gene expression. Here, we performed nascent and mature transcript sequencing after the acute degradation of 12 ma...
ORGANISM(S): Mus <genus> 
PXD035866 |
ProteomicsCAF-1 promotes HIV-1 latency by leading the formation of phase-separated suppressive nuclear bodies
HIV-1 latency is a major obstacle to achieve a functional cure for AIDS. To eradicate the viral reservoir, one of the strategies is to specifically reactivate HIV-1-infected cells and followed by elimination with potent immune surveillance. However, present latency-reversing agents (LRAs) are quite ...
ORGANISM(S): Homo Sapiens 
2021-02-09 | PXD024172 |
ProteomicsCBX4 contributes to HIV-1 latency by forming phase-separated nuclear bodies and SUMOylating EZH2
Molecular mechanisms of HIV-1 latency have been studied extensively to achieve a functional cure for the acquired immunodeficiency syndrome (AIDS). To develop more promising latency-reversing agents (LRAs) to efficiently reactivate the latent reservoir which is subsequently eliminated by immune surv...
ORGANISM(S): Homo Sapiens 
2022-01-14 | PXD031011 |
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