Sort   by:  
 Page size 
MetabolomicsCD73 inhibitor AB680 suppresses glioblastoma in mice by inhibiting purine metabolism and promoting P2RY12<sup>+</sup> microglia transformation.
CD73 (ecto-5'-nucleotidase) is a metabolic immune checkpoint that dephosphorylates AMP to produce adenosine. Adenosine plays a pivotal role in immunosuppressive tumor microenvironment (TME) through adenosine receptors expressed on various immune cells. AB680, a specific CD73 inhibitor, is currently ...
2025-08-04 | MTBLS11084 | MetaboLights
ProteomicsHuman VSMC infected with Ad-CEMIP and immunoprecipitated with anti-CEMIP for proteomic analysis
HASMCs were infected with Ad-CEMIP. Whole cell lysates were obtained from 5×108 cells. CEMIP or IgG antibodies are added to capture CEMIP complexes in cell lysates. Agarose beads were washed with IP buffer, CEMIP antibody-binding complexes were captured by adding agarose beads to cell lysates, and n...
ORGANISM(S): Homo Sapiens 
2025-03-20 | PXD062060 |
ProteomicsSMC-CemipKO aortic media immunoprecipitated with anti-MLC20 antibodies for proteomic
Protein was extracted from the aortic media of 8-week-old SMC-CemipKO and Cemipflox/flox mice. Whole-cell lysates were immunoprecipitated with anti-MLC20 antibodies for proteomic analysis. Mass spectrometry identified top 10 MLC20-binding proteins as listed.
ORGANISM(S): Mus Musculus 
2025-03-18 | PXD062008 |
ProteomicsDiscovering sORF-encoded Peptides Associated with Secondary Metabolism in Streptomyces
To investigate the effect of small peptides up to 100aa on the regulation of secondary metabolite synthesis during the fermentation of this strain S187. Differential expression of peptides within 100aa at different growth time points of strain S187.
ORGANISM(S): Streptomyces 
2022-11-17 | PXD038189 |
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
UnknownA benchmark of expert-level academic questions to assess AI capabilities.
Not available
S-EPMC12851929 | biostudies-literature
UnknownElective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans.
Not available
S-EPMC7272903 | biostudies-literature
Sort   by:  
 Page size