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UnknownEffects of 17β-Estradiol Pollution on Microbial Communities and Methane Emissions in Aerobic Water Bodies.
Not available
S-EPMC11126138 | biostudies-literature
UnknownPhylloquinone Attenuates Oxygen-Glucose Deprivation-induced Neuronal Injury by Inhibiting Ferroptosis via the xCT/GPX4 Pathway.
Not available
S-EPMC12657559 | biostudies-literature
UnknownMultipronged heat-exchanger based on femtosecond laser-nano/microstructured Aluminum for thermoelectric heat scavengers.
Not available
S-EPMC7453914 | biostudies-literature
ProteomicsProteomic Sequencing of Blood Across Different Growth Stages of Deer Antler
Aim to detect the differential protein expression of plasma samples collected in different stage using DIA quantitative proteome technology.
ORGANISM(S): Cervus Nippon 
2024-06-06 | PXD052882 |
ProteomicsDe novo pyrimidine biosynthetic complexes support cancer cell proliferation and ferroptosis defense
De novo pyrimidine biosynthesis is achieved by cytosolic enzymes, CAD and UMPS, and mitochondrial DHODH. However, how these enzymes are orchestrated remains enigmatical. Here, we show that cytosolic aspartate-producing GOT1 clusters with CAD and UMPS. This cytosolic cluster then connects with DHODH,...
ORGANISM(S): Homo Sapiens 
2023-03-22 | PXD041017 |
ProteomicsPhosphoproteomics reveal that phosphorylation of MTDH by CDK5 inhibits protein synthesis in microglia
Our findings identified 335 phosphorylation sites on 234 proteins as potential CDK5 substrates in microglia based on the reported sequence motif
ORGANISM(S): Mus Musculus 
2024-03-08 | PXD050465 |
ProteomicsCirculating ACE2-expressing Extracellular Vesicles as an Innate Antiviral Response and A Decoy Therapy to Block Broad Strains of SARS-CoV-2
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)has caused the pandemic of the coronavirus induced disease 2019 (COVID-19) with 216 million cases and 4.5 million deathsas of September 2021.Thathas been exacerbated by mutated variants such as α, β, and with high infection rates and i...
ORGANISM(S): Homo Sapiens (human) 
2021-12-10 | PXD029662 | JPOST Repository
ProteomicsPHGDH Arginine Methylation by PRMT1 Promotes Serine Synthesis and Represents a Therapeutic Vulnerability in Hepatocellular Carcinoma
Serine synthesis is crucial for tumor growth and survival, but its regulatory mechanism in cancer remains elusive. Here, we found that R236 methylation of PHGDH promotes its activity and stimulates serine synthesis in hepatocellular carcinoma.
ORGANISM(S): Homo Sapiens 
2022-07-28 | PXD035061 |
ProteomicsPHGDH Arginine Methylation by PRMT1 Promotes Serine Synthesis and HCC Growth
Serine synthesis is crucial for tumor growth and survival, but its regulatory mechanism in cancer remains elusive. Phosphoglycerate dehydrogenase (PHGDH) is the first rate-limiting enzyme in serine biosynthesis pathway. Here, we analyzed immunoprecipitated PHGDH from human HEK293T cells by liquid ch...
ORGANISM(S): Homo Sapiens 
2022-07-29 | PXD035287 |
UnknownBurden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
Not available
S-EPMC12535840 | biostudies-literature
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