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MetabolomicsLaser-assisted rapid evaporative ionisation mass spectrometry (LA-REIMS) as a metabolomics platform in cervical cancer screening

BACKGROUND: The introduction of high-risk human papillomavirus (hrHPV) testing as part of primary cervical screening is anticipated to improve sensitivity, but also the number of women who will screen positive. Reflex cytology is the preferred triage test in most settings but ha...

2022-02-15 | MTBLS1371 | MetaboLights
TranscriptomicsComparative genomic hybridization of kidney samples from Wilms tumor patients to accurately map 1p13 breakpoints
Wilms tumour karyotypes frequently exhibit recurrent, large-scale chromosomal imbalances, among the most common of which are concurrent loss of 1p and gain of 1q. We have previously identified a novel breakpoint at 1p13 by 1Mb-spaced array CGH, and undertook a fine-tiling oligonucleotide array appro...
ORGANISM(S): Homo sapiens 
2007-03-21 | E-TABM-155 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of kidney samples from Wilms tumor patients to examine down- and up-regulation of genes either side of 1p13 breakpoints
Wilms tumour karyotypes frequently exhibit recurrent, large-scale chromosomal imbalances, among the most common of which are concurrent loss of 1p and gain of 1q. We have previously identified a novel breakpoint at 1p13 by 1Mb-spaced array CGH, and undertook a fine-tiling oligonucleotide array appro...
ORGANISM(S): Homo sapiens 
2007-03-21 | E-TABM-164 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of purified populations of normal human breast luminal and myoepithelial cells
Purified populations of normal human breast luminal and myoepithelial cells were compared with cDNA microarray analysis.
ORGANISM(S): Homo sapiens 
2004-05-04 | E-MEXP-36 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis root developmental zones after iron deficiency (-Fe) treatment
To gain a genome-scale understanding of the role that developmental processes play in regulating stimulus response, we examined the effect of -Fe stress on gene expression along the longitudinal axis of the root. Since roots grow from stem cells located near the tip, the position of cells along the...
ORGANISM(S): Arabidopsis thaliana 
2008-06-11 | E-GEOD-10497 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of normal and malignant human breast epithelial cells
Multiple genome-wide microarrays have been used to analyse the transcriptomes of immunomagnetically separated normal human luminal epithelial and myoepithelial cells, as well as primary malignant breast epithelial cells.
ORGANISM(S): Homo sapiens 
2006-09-29 | E-TABM-66 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis roots after protoplasting and FACS and exposure to iron deficiency (-Fe)
In order to estimate the effects of protoplasting and FACS sorting procedures on -Fe regulated gene expression we generated expression profiles for whole roots that had been treated with -Fe for 24 hours and for roots that were protoplasted and FACS sorted after the initial 24 hour -Fe treatment. Li...
ORGANISM(S): Arabidopsis thaliana 
2008-06-11 | E-GEOD-10496 | biostudies-arrayexpress
TranscriptomicsA temperature-responsive network links cell shape and virulence traits in a primary fungal pathogen -- RNAi mutants (2)
The ability to grow at host temperature is a critical trait for most pathogenic microbes of humans. Thermally dimorphic fungal pathogens, including Histoplasma capsulatum, are a class of soil fungi that undergo a dramatic change in cell shape and virulence gene expression in response to host tempera...
ORGANISM(S): Ajellomyces capsulatus 
2013-06-14 | E-GEOD-46939 | biostudies-arrayexpress
TranscriptomicsA temperature-responsive network links cell shape and virulence traits in a primary fungal pathogen -- RNAi mutants (1)
The ability to grow at host temperature is a critical trait for most pathogenic microbes of humans. Thermally dimorphic fungal pathogens, including Histoplasma capsulatum, are a class of soil fungi that undergo a dramatic change in cell shape and virulence gene expression in response to host tempera...
ORGANISM(S): Ajellomyces capsulatus 
2013-06-14 | E-GEOD-46938 | biostudies-arrayexpress
TranscriptomicsA temperature-responsive network links cell shape and virulence traits in a primary fungal pathogen -- T-DNA mutants (1)
The ability to grow at host temperature is a critical trait for most pathogenic microbes of humans. Thermally dimorphic fungal pathogens, including Histoplasma capsulatum, are a class of soil fungi that undergo a dramatic change in cell shape and virulence gene expression in response to host tempera...
ORGANISM(S): Ajellomyces capsulatus 
2013-06-14 | E-GEOD-46936 | biostudies-arrayexpress
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