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TranscriptomicsAneuploidy-induced cellular stresses limit autophagic degradation.
An unbalanced karyotype, a condition known as aneuploidy, has a profound impact on cellular physiology and is a hallmark of cancer. Determining how aneuploidy affects cells is thus critical to understanding tumorigenesis. Here we show that aneuploidy interferes with the degradation of autophagosomes...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-60570 | biostudies-arrayexpress
UnknownPredicting antidisease immunity using proteome arrays and sera from children naturally exposed to malaria.
Not available
S-EPMC4188993 | biostudies-literature
TranscriptomicsJarid2 regulates hematopoietic stem cell function by acting with Polycomb Repressive Complex 2
Polycomb Repressive Complex 2 (PRC2) has been shown to play a key role in hematopoietic stem and progenitor cell (HSPC) function. Analyses of mouse mutants harboring deletions of core components have implicated PRC2 in fine-tuning multiple pathways that instruct HSPC behavior, yet how PRC2 is target...
ORGANISM(S): Mus musculus 
2015-04-02 | E-GEOD-60808 | biostudies-arrayexpress
UnknownA small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity.
Not available
S-EPMC10374545 | biostudies-literature
TranscriptomicsComparison of GFP- and Nurr1-infected ES-cell derived neurons
ES cell-derived neurons of forebrain identity were isolated by magnetic sorting, cultured for 7 days and transduced with either Nurr1 or eGFP lentivirus. After an additional 12 h in culture, mRNA was isolated and subjected to microarray analysis. The raw data have been provided in CEL format The p...
ORGANISM(S): Mus musculus 
2010-06-08 | E-GEOD-20392 | biostudies-arrayexpress
UnknownInferring structural variant cancer cell fraction.
Not available
S-EPMC7002525 | biostudies-literature
UnknownSystematic assessment of long-read RNA-seq methods for transcript identification and quantification.
Not available
S-EPMC10402094 | biostudies-literature
UnknownEffect of Aspirin on Disability-free Survival in the Healthy Elderly.
Not available
S-EPMC6426126 | biostudies-literature
UnknownEffect of Aspirin on All-Cause Mortality in the Healthy Elderly.
Not available
S-EPMC6433466 | biostudies-literature
UnknownTwo phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
Not available
S-EPMC4159618 | biostudies-literature
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