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GenomicsDynamic changes of DNA methylome and hydroxymethylome during neural differentiation of hES cell (hMeDIP-Seq and MBD-Seq)
DNA methylation and hydroxymethylation have been implicated in normal development and differentiation, but our knowledge about the genome-wide distribution of 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) during cellular differentiation remains limited. Using in vitro model system of gra...
ORGANISM(S): Homo sapiens 
2013-11-04 | E-GEOD-38214 | biostudies-arrayexpress
TranscriptomicsDynamic changes of DNA methylome and hydroxymethylome during neural differentiation of hES cells (Methylation BeadChip)
DNA methylation and hydroxymethylation have been implicated in normal development and differentiation, but our knowledge about the genome-wide distribution of 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) during cellular differentiation remains limited. Using in vitro model system of gra...
ORGANISM(S): Homo sapiens 
2013-11-04 | E-GEOD-38216 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of microRNAs and their targets involving in leaf senescence of rice
Enhancing grain production of rice (Oryza sativa L.) is a top priority in ensuring food security for human being. One approach to increase yield is to delay leaf senescence and to extend the available time for photosynthesis. microRNAs (miRNAs) are key regulators for aging and cellular senescence in...
ORGANISM(S): Oryza sativa 
2015-01-01 | E-GEOD-62200 | biostudies-arrayexpress
TranscriptomicsExpression profile of liver samples from subjects at the time of Roux en Y gastric bypass surgery.
To map the genetics of gene expression in metabolically relevant tissues and investigate the diversity of expression SNPs (eSNPs) in multiple tissues from the same individual, we collected four tissues from approximately 1,000 patients undergoing Roux-en-y gastric bypass and clinical traits associat...
ORGANISM(S): Homo sapiens 
2011-04-01 | E-GEOD-24293 | biostudies-arrayexpress
GenomicsDNA-Seq of human hepatocellular carcinoma and adjacent tissues to determine differetiatial expression of microRNA
Determine differetiatial expression of micro RNA in paired human hepatocellular tumor tissues and their adjacent cirrosis tissues by SOLiD sequencing. http://www.appliedbiosystems.com/absite/us/en/home/applications-technologies/solid-next-generation-sequencing/small-rna-analysis.html Matrix with res...
ORGANISM(S): Homo sapiens 
2011-10-01 | E-MTAB-511 | biostudies-arrayexpress
TranscriptomicsExpression profile of omental adipose samples from subjects at the time of Roux en Y gastric bypass surgery.
To map the genetics of gene expression in metabolically relevant tissues and investigate the diversity of expression SNPs (eSNPs) in multiple tissues from the same individual, we collected four tissues from approximately 1,000 patients undergoing Roux-en-y gastric bypass and clinical traits associat...
ORGANISM(S): Homo sapiens 
2011-04-01 | E-GEOD-24294 | biostudies-arrayexpress
TranscriptomicsExpression profile of subcutaneous adipose samples from subjects at the time of Roux en Y gastric bypass surgery.
To map the genetics of gene expression in metabolically relevant tissues and investigate the diversity of expression SNPs (eSNPs) in multiple tissues from the same individual, we collected four tissues from approximately 1,000 patients undergoing Roux-en-y gastric bypass and clinical traits associat...
ORGANISM(S): Homo sapiens 
2011-04-01 | E-GEOD-24297 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of E. faecalis ORGR1F transconjugants mated with V583 to determine the amount of DNA transfered between strains
Comparative genome hybridization of transconjugants of E. faecalis OG1RF mated with V583. The total DNA of transconjugants was compared with wildtype strains to ascertain the amount of DNA that was transferred from E. faecalis V583 to E. faecalis OG1RF.
ORGANISM(S): Enterococcus faecalis 
2009-05-08 | E-MEXP-2135 | biostudies-arrayexpress
TranscriptomicsGene transcription profiles showing early systemic response to E. coli (k2bh2) infection in bovine liver
We studied the response to infection and associated perturbations to the bovine liver’s normal function by examining gene transcription data from liver biopsies collected following an E. coli infection in the udder of primiparous dairy cows. This is the first study to examine gene transcription resp...
ORGANISM(S): Bos taurus 
2012-01-01 | E-GEOD-25319 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis plants after heat shock or treatment with HSP90 inhibitors (geldanamycin and radicicol)
Effect of heat shock or HSP90 inhibitors (geldanamycin and radicicol) on wild type Arabidopsis thaliana.
ORGANISM(S): Arabidopsis thaliana 
2007-06-01 | E-ATMX-12 | biostudies-arrayexpress
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