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MetabolomicsMetabolic Dynamics of In Vitro CD8+ T Cell Activation

CD8+ T cells detect and kill virally infected or cancerous cells. When activated from their naïve state, T cells undergo a complex transition, including major metabolic reprogramming. Detailed resolution of metabolic dynamics of a wide range of metabolites is needed to advance the field of immuno...

2021-06-02 | MTBLS2145 | MetaboLights
Genomicsp53 Chip-Seq in U2OS treated with UV
We report that TAF1 phosphorylates p53 at Thr55 on the p21 promoter and this phosphorylation leads to dissociation of p53 from the promoter. Indeed, ChIP-Seq analysis reveals p53 undergoes promoter dissociation at a global level after response to DNA damage, underscoring general nature of the regul...
ORGANISM(S): Homo sapiens 
2014-10-10 | E-MTAB-1988 | biostudies-arrayexpress
UnknownDietary Phytochemicals that Can Extend Longevity by Regulation of Metabolism.
Not available
S-EPMC8756168 | biostudies-literature
UnknownNetwork Representations of Facial and Bodily Expressions: Evidence From Multivariate Connectivity Pattern Classification.
Not available
S-EPMC6828617 | biostudies-literature
TranscriptomicsExpression data from synchronized L4 C. elegans during starvation
The endoplasmic reticulum (ER) is an organelle associated with lipid metabolism. However, the involvement of the ER in nutritional status-dependent energy homeostasis is largely unknown. The results of this study demonstrate that IRE-1, an ER protein known to be involved in the unfolded protein resp...
ORGANISM(S): Caenorhabditis elegans 
2010-05-08 | E-GEOD-15656 | biostudies-arrayexpress
UnknownPhylogenetic prioritization of HIV-1 transmission clusters with viral lineage-level diversification rates.
Not available
S-EPMC9311310 | biostudies-literature
TranscriptomicsMurine skin gene expression analysis of skin-specific Scd1-deficient and control mice
To help elucidate the metabolic changes in the skin that contribute to the obesity resistance and skin pathology in mice lacking Scd1, we performed microarray analysis of skin gene expression in male skin Scd1 knockout (SKO) and Scd1 flox/flox control (Lox) mice fed a standard rodent diet. We identi...
ORGANISM(S): Mus musculus 
2011-05-09 | E-GEOD-24243 | biostudies-arrayexpress
UnknownImpact of SARS-CoV-2 lockdown on expansion of HIV transmission clusters among key populations: A retrospective phylogenetic analysis.
Not available
S-EPMC9500205 | biostudies-literature
TranscriptomicsMycobacterium avium subsp. paratuberculosis K-10 & phoPR comparison
To compare the transcriptional profile of K-10 and phoPR in the log phase, and to find out the effects of phoPR on MAP gene expression. There are three replicates from K-10 as the control samples, and three replicates from phoPR used to examine the differences.
ORGANISM(S): Mycobacterium avium subsp. paratuberculosis 
2016-03-01 | E-GEOD-71291 | biostudies-arrayexpress
UnknownTheoretical and experimental assessment of degenerate primer tagging in ultra-deep applications of next-generation sequencing.
Not available
S-EPMC4081055 | biostudies-literature
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