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Proteomicsplasma-derived exosomes from healthy and osteosarcoma
Identification of proteins from plasma-derived exosomes of from healthy controls and osteosarcoma patients by LC-MS/MS in label-free quantification.
ORGANISM(S): Homo sapiens (Human) 
2021-07-02 | PXD024072 | Pride
Lc-ms/ms Exosomes Proteomics analysis 
ProteomicsMolecular Responses During Bacterial Filamentation Induced by Antibiotics
Bacterial filamentation is one of the most important bacterial SOS responses to antibiotic drugs and contributes to the development of antimicrobial resistance. Understanding the mechanism of the bacterial SOS response is crucial to control the development of antibiotic-resistant bacteria. We uncove...
ORGANISM(S): Escherichia Coli 
2023-01-04 | PXD039235 |
ProteomicsOnline Microfluidics Mass Spectrometry Reveals Molecular Responses of Bacterial Filamentation and Inhibition Methods of Drug Resistant Bacteria
Filamentation is one of the self-saving responses and a survival strategy of bacteria in the circumstance of antibiotics. Understanding the molecular mechanism of filamentation can lead to the development of new inhibition methods for antibiotic-resistant bacteria. In this work, we develop an online...
ORGANISM(S): Escherichia Coli 
2021-02-26 | PXD024394 |
TranscriptomicsRNA-seq analysis of gene expression patterns responding to TSA treatment during hESC neural differentiation
We report the differential roles of an HDAC inhibitor-TSA during hESC nerual commitment. In the initiation of hESC differentiation, TSA could inhibit the downregulation of pluripotency genes to maintain pluripotency, whereas in the neural commitment stage, TSA could promote neural gene expression to...
ORGANISM(S): Homo sapiens 
2015-03-11 | E-GEOD-66777 | biostudies-arrayexpress
ProteomicsMetaproteomics characterizes human gut microbiota function in colorectal cancer
Alterations in gut microbiota have been implicated in the pathogenesis of Colorectal Cancer (CRC). Here we collected fecal samples from 14 CRC patients and 14 healthy volunteer cohorts, and characterized their microbiota using label-free quantitative metaproteomics method. We have quantified 30,062 ...
ORGANISM(S): Homo Sapiens 
2020-02-23 | PXD013386 |
TranscriptomicsInterplay between AP-1 and ERalpha in regulating gene expression and proliferation networks in breast cancer cells
Estrogen receptor alpha (ERalpha) is a ligand-dependent transcription factor that plays an important role in breast cancer. Estrogen-dependent gene regulation by ERalpha can be mediated by interaction with other DNA-binding proteins, such as activator protein-1 (AP-1). The nature of such interaction...
ORGANISM(S): Homo sapiens 
2012-08-05 | E-GEOD-36586 | biostudies-arrayexpress
MetabolomicsMulti-omic Profiling of Multi-Biosamples Reveals the Role of Amino Acid and Nucleotide Metabolism in Endometrial Cancer
Endometrial cancer (EC) is one of the most common gynecological cancers. Finding biomarkers of EC can support its diagnosis in a non- or minimally-invasive way. In this work, we integrated metabolomics and proteomics for the analysis of multiple types of biosamples to gain a more comprehensive view ...
2022-03-28 | MTBLS3935 | MetaboLights
TranscriptomicsComparison of endocrine enriched genes in islet beta cells versus induced beta cells
Endocrine enriched genes in adult islet beta cells were identified and compared with that of induced beta cells (with M3 transcription factors) in adult. The control sample is non-beta pancreatic cells. Gene expression profile comparison of 3 samples, 3 independent repeats for each sample indicate ...
ORGANISM(S): Mus musculus 
2008-07-08 | E-GEOD-12025 | biostudies-arrayexpress
ProteomicsSerum Peptidome Profiles Immune Response of COVID-19 Vaccine Administration
The study shows the promise of MALDI-TOF MS-based serum peptidome analysis for the assessment of immune responses activated by COVID-19 vaccination, and discovered a panel of serum peptides biomarkers for COVID-19 vaccination and for NAbs generation. The method developed in this study can help not o...
ORGANISM(S): Homo Sapiens 
2022-08-19 | PXD036159 |
UnknownPan-Genome Analysis Reveals Local Adaptation to Climate Driven by Introgression in Oak Species.
Not available
S-EPMC12042805 | biostudies-literature
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