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TranscriptomicsTranscription profiling of S. cerevisiae wild type and cyclin mutant
Yeast cell cycle transcription dynamics in two S. cerevisae strains: BF264-15DU (MATa ade1 his2 leu2-3, 112 trp1-1 ura3Dns, bar1) [referred to as wild type] and a mutant of the wild type strain, clb1,2,3,4,5,6 GAL1-CLB1, [referred to as cyclin mutant] that does not express S-phase and mitotic cyclin...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-20 | E-GEOD-8799 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse wild type and Lim1-null renal vesicles microdissected from embryonic day 12.5 kidneys
The Lim1 gene has essential functions during several stages of kidney development. In particular, a tissue specific knockout in the early metanephric mesenchyme results in the formation of the earliest nephron precursor, the renal vesicle, but failure of this structure to progress to the next stage,...
ORGANISM(S): Mus musculus 
2007-12-12 | E-GEOD-7257 | biostudies-arrayexpress
TranscriptomicsSalicylic acid-induced gene expression in wild-type Col-0 and mutant upl3-4 Arabidopsis thaliana plants.
Activation of plant immunity is associated with dramatic transcriptome reprogramming to prioritise immune responses over normal cellular functions. Changes in gene expression are coordinated by the immune hormone salicylic acid (SA). Here we investigated the involvement of the HECT-type ligase Ubiqu...
ORGANISM(S): Arabidopsis thaliana 
2018-11-09 | E-MTAB-7374 | biostudies-arrayexpress
GenomicsMDACC-endo
Data Access Committee EGAC00001000066
EGAC00001000066 | EGA
TranscriptomicsStreptococcus gordonii gene response to the binding of human salivary amylase.
Streptococcus gordonii, an important primary colonizer of dental plaque biofilm, specifically binds to salivary amylase via the surface-associated amylase-binding protein A (AbpA). We hypothesized that amylase binding to S. gordonii modulates expression of chromosomal genes, which could influence ba...
ORGANISM(S): Streptococcus gordonii str. Challis 
2011-09-02 | E-GEOD-31830 | biostudies-arrayexpress
TranscriptomicsDNA damage Signaling Pathway PCR Array to profile the expression of human genes regulating in the DNA damage response (DDR) network
Human DNA Damage Signaling Pathway RT2 Profiler Array Kit (Qiagen, Valencia, CA) was used to profile the expression of key genes involved in the DDR network as per the manufacturer’s instructions. U937 cells were incubated with PXD-101 +/- MLN4924 for 16 h, after which the RT2 ProfilerTM DNA damag...
ORGANISM(S): Homo sapiens 
2016-02-05 | E-GEOD-77560 | biostudies-arrayexpress
UnknownBiomarker Testing Disparities in Metastatic Colorectal Cancer.
Not available
S-EPMC11227072 | biostudies-literature
TranscriptomicsArray results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol
RELEVANCE: Smith-Lemli-Opitz syndrome (SLOS) is a human disease caused by mutations in the gene coding for the enzyme DHCR7 (7-dehydrocholesterol (7DHC) reductase), which catalyzes the final step of cholesterol biosynthesis. Accumulated 7DHC in tissues and body fluids of SLOS patients gives rise t...
ORGANISM(S): Mus musculus 
2021-03-20 | E-MTAB-10055 | biostudies-arrayexpress
GenomicsChIP seq for p63, H3K27ac and BRD4 in L3.6pl, BxPC-3 pancreatic cancer cell lines and ChIP-seq of H3K27ac and BRD4 in Panc-1 pancreatic cell line
We investigated the regions that are occupied by deltaNp63 in BxPC-3 and L3.6pl and identification of super enhancers in different pancreatic cancer cell lines. Thereby, we identified a group of 45 super enhancers that are associated with poorer prognosis and are highly dependent on deltaNp63.
ORGANISM(S): Homo sapiens 
2018-12-18 | E-MTAB-7034 | biostudies-arrayexpress
TranscriptomicsRNAi knock down of four Argonaute paralogs (AGO1, AGO2, PIWI and Aubergine) and the microRNA-processing enzyme Drosha in Drosophila
RNA silencing pathways are conserved gene regulation mechanisms that lead to degradation, translational repression or transcriptional silencing of target-transcripts selected based on complementarity with small RNA molecules. The fraction of the genome regulated by these pathways has not been establ...
ORGANISM(S): Drosophila melanogaster 
2006-11-20 | E-MEXP-295 | biostudies-arrayexpress
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