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MetabolomicsShort-Term Clinical Response and Changes in the Fecal Microbiota and Metabolite Levels in Patients with Crohn's Disease After Stem Cell Infusions
Recent studies have shown a close relationship between the gut microbiota and Crohn's disease (CD). This study aimed to determine whether mesenchymal stem cell (MSC) treatment alters the gut microbiota and fecal metabolite pathways and to establish the relationship between the gut microbiota and fec...
2025-07-03 | MTBLS6288 | MetaboLights
MetabolomicsIntestinal accumulation of microbiota-produced succinate caused by loss of microRNAs leads to diarrhea in weanling piglets
Diarrheal disease is a common health problem with complex causality. Although diarrhea is accompanied by disturbances in microbial diversity, how gut microbes are involved in the occurrence of diarrhea remains largely unknown. Here, using a pig model of post-weaning stress-induced diarrhea, we aim t...
2023-01-09 | MTBLS4040 | MetaboLights
TranscriptomicsEffect of Integrin-aBb2 on transcription in 2d or 3d.
M21 or M21L cells were grown either in 2d (on plastic) or in a 3d-collagen model. 2x2 design, in triplicate
ORGANISM(S): Homo sapiens 
2012-07-10 | E-GEOD-34219 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of compound-treated cells
Huh7.5.1 cells were incubated for 48 h with LY-411575, JNJ-1802, NITD-688, and NITD-008 at their respective EC90 concentrations against DENV: 10 nM, 0.1 nM, 7 nM, and 1.3 μM. Cells treated with DMSO served as controls. Three replicates for each treatment.Total RNA was extracted using the RNeasy Mini...
ORGANISM(S): Homo sapiens 
2024-12-29 | E-MTAB-14694 | biostudies-arrayexpress
UnknownIrisin enhances chondrogenic differentiation of human mesenchymal stem cells via Rap1/PI3K/AKT axis.
Not available
S-EPMC9351134 | biostudies-literature
TranscriptomicsTranscription profiling of human MCF7 time-series upon RITA treatment.
Targeting “oncogene addiction” is a promising strategy for anti-cancer therapy. Here, we report a potent inhibition of crucial oncogenes by p53 upon reactivation with small molecule RITA in vitro and in vivo. RITA-activated p53 unleashes transcriptional repression of anti-apoptotic proteins Mcl-1, ...
ORGANISM(S): Homo sapiens 
2009-05-15 | E-GEOD-13291 | biostudies-arrayexpress
ProteomicsChemically Engineered Antibodies for Autophagy-based Receptor Degradation.
Quantitative proteomic analysis raw data for the manuscript entitled “Chemically Engineered Antibodies for Autophagy-based Receptor Degradation”.
ORGANISM(S): Homo Sapiens 
2024-10-12 | PXD056766 |
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