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GenomicsTET1 is a maintenance DNA demethylase that prevents methylation spreading in adult cells [MeDIP-Seq]
We report that full length TET1 (TET1-FL) overexpression fails to induce global DNA demethylation in HEK293T cells. The preferential binding of TET1-FL to hypomethylated CpG islands (CGIs) through its CXXC domain leads to its inhibited 5-hydroxymethylcytosine (5hmC) production as methylation level i...
ORGANISM(S): Homo sapiens 
2014-06-04 | E-GEOD-44036 | biostudies-arrayexpress
UnknownEmbolism of coronary, cerebral, and limb arteries resulting from infective endocarditis of a prosthetic aortic valve: a clinical case report.
Not available
S-EPMC12764105 | biostudies-literature
GenomicsTET1 is a maintenance DNA demethylase that prevents methylation spreading in adult cells [DREAM]
We report that full length TET1 (TET1-FL) overexpression fails to induce global DNA demethylation in HEK293T cells. The preferential binding of TET1-FL to hypomethylated CpG islands (CGIs) through its CXXC domain leads to its inhibited 5-hydroxymethylcytosine (5hmC) production as methylation level i...
ORGANISM(S): Homo sapiens 
2014-06-04 | E-GEOD-44038 | biostudies-arrayexpress
UnknownTransitional Dynamics of Sarcopenia and Associations of Nutritional Indices with State Transitions in Chinese aged ≥ 50.
Not available
S-EPMC12275563 | biostudies-literature
GenomicsArchitecture of Epigenetic Reprogramming Following Twist1 Mediated Epithelial-Mesenchymal Transition [ChIP-seq]
Purpose: to characterize epigenetic changes following Twist1 mediated Epithelial-Mesenchymal Transition in human Methods: we characterized the epigenetic and transcriptome landscapes using whole genome transcriptome analysis by RNA-seq, DNA methylation by digital restriction enzyme analysis of meth...
ORGANISM(S): Homo sapiens 
2013-12-10 | E-GEOD-53023 | biostudies-arrayexpress
GenomicsArchitecture of Epigenetic Reprogramming Following Twist1 Mediated Epithelial-Mesenchymal Transition
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-12-10 | E-GEOD-53026 | biostudies-arrayexpress
GenomicsArchitecture of Epigenetic Reprogramming Following Twist1 Mediated Epithelial-Mesenchymal Transition [DREAM-seq]
Purpose: to characterize epigenetic changes following Twist1 mediated Epithelial-Mesenchymal Transition in human Methods: we characterized the epigenetic and transcriptome landscapes using whole genome transcriptome analysis by RNA-seq, DNA methylation by digital restriction enzyme analysis of meth...
ORGANISM(S): Homo sapiens 
2013-12-10 | E-GEOD-53025 | biostudies-arrayexpress
UnknownZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA.
Not available
S-EPMC4359216 | biostudies-literature
TranscriptomicsConserved Topological Domains in Mammalian Genomes Identified by High-resolution Analysis of Chromatin Interactions
The spatial organization of the genome is intimately linked to its biological function, yet our understanding of higher order genomic structure is limited. Here we present high-resolution analyses of chromosomal organization in pluripotent and differentiated human and murine cell types determined u...
ORGANISM(S): Mus musculus 
2012-04-10 | E-GEOD-35156 | biostudies-arrayexpress
ProteomicsProteome of the fungus Phoma macdonaldii, the causal agent of black stem in sunflower
Phoma macdonaldii causes black stem in sunflower, which severely affects both the yield and quality of sunflowers including weight and oil content of seeds. In this study, a global proteomic analysis of P. macdonaldii was performed in order to facilitate a better understand of the biological and pat...
ORGANISM(S): Plenodomus Lindquistii 
2020-01-17 | PXD017157 |
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