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GenomicsGenome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage [ChIP-Seq]
Mouse hair follicles undergo synchronized cycles. Cyclical regeneration and hair growth is fueled by stem cells (SCs). During the rest phase, the HF-SCs remain quiescent due to extrinsic inhibitory signals within the niche. As activating cues accumulate, HF-SCs become activated, proliferate, and gro...
ORGANISM(S): Mus musculus 
2011-09-02 | E-GEOD-31239 | biostudies-arrayexpress
GenomicsNfatc1 Orchestrates Aging in Hair Follicle Stem Cells
Mouse hair follicles undergo synchronized cycles. Cyclical regeneration and hair growth is fueled by hair follicle stem cells (HFSCs). We used ChIP-seq to unfold genome-wide chromatin landscapes of Nfatc1 and dissect the biological relevence of its upstream BMP signaling in HFSC aging. Telogen quies...
ORGANISM(S): Mus musculus 
2013-11-14 | E-GEOD-52328 | biostudies-arrayexpress
GenomicsGenome-wide mapping of REST-bound sites in human CD4+ T cells
We performed ChIP-seq to identify genome-wide REST (NRSF) binding in the human CD4+ T cells. The data were compared to REST occupancy in additional 15 human cell types analyzed by the ENCODE project (GSE32465) in order to study the dynamics and context-dependent functions of REST-chromatin interacti...
ORGANISM(S): Homo sapiens 
2014-08-06 | E-GEOD-49570 | biostudies-arrayexpress
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