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ProteomicsControl of protein accumulation by the LON2 peroxisomal protease and autophagy
Peroxisomes are membrane-bound eukaryotic organelles that house essential metabolic pathways. Many of these pathways generate damaging reactive oxygen species (ROS) that also function as signaling molecules. In Arabidopsis thaliana, damaged or obsolete peroxisomal proteins can be degraded by the LON...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-05-06 | PXD022921 | Pride
Protease Peroxisomes Pexophagy Chaperone 
TranscriptomicsCorrelation of transcriptomic responses and metal bioaccumulation in Mytilus edulis L. reveals early indicators of stress
Marine biomonitoring programs in the U.S. and Europe have historically relied on monitoring tissue concentrations of bivalves to monitor contaminant levels and ecosystem health. By integrating M-bM-^@M-^Xomic methods with these tissue residue approaches we can uncover mechanistic insight to help li...
ORGANISM(S): Mytilus edulis 
2014-06-20 | E-GEOD-58649 | biostudies-arrayexpress
no omics definedGene expression profiles of high and low immune responder Holstein cows
The study explores the genetic basis of high or low antibody (Ab) and cell (DTH)-mediated immune responses in Canadian Holstein cows using microarray hybridization to an in-house immune-endocrine cDNA microarray Keywords: immune response comparison The study uses a common reference design for the mi...
ORGANISM(S): Bos taurus 
2008-05-15 | E-GEOD-11454 | biostudies-arrayexpress
TranscriptomicsDifferential Expression of Ove26(Diabetic) vs FVB(Nondiabetic) mice
Objective – Previous studies showed that genetic deletion or pharmacological blockade of the Receptor for Advanced Glycation Endproducts (RAGE) prevents the early structural changes in the glomerulus associated with diabetic nephropathy (DN). To overcome limitations of mouse models that lack the pr...
ORGANISM(S): Mus musculus 
2011-02-22 | E-GEOD-20844 | biostudies-arrayexpress
TranscriptomicsSystems Modeling of the Rho Signaling Network
Describing the architecture of robust, nonlinear cell signaling networks is essential to gain a predictive understanding of cellular behavior. The structure of the Drosophila Rho-signaling network, comprised of Rho-family GTPases, RhoGTP Exchange Factors (RhoGEFs), and RhoGTPase Activating Proteins...
ORGANISM(S): Drosophila melanogaster 
2012-12-31 | E-GEOD-18307 | biostudies-arrayexpress
UnknownMutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects.
Not available
S-EPMC4986528 | biostudies-literature
TranscriptomicsGene expression profiles of Hyalella azteca populations with different pyrethroid sensitivities
The goal of the study was to investigate gene expression differences in Hyalella azteca exposed to pyrethroid insecticides and compare a laboratory strain to a wild population believed to be resistant to the pesticides. H. azteca reared in the laboratory at the University of CA, Berkeley (UCB) were...
ORGANISM(S): Hyalella azteca 
2013-07-17 | E-GEOD-48943 | biostudies-arrayexpress
TranscriptomicsAssessment of chemical mixtures and ground water effects on Daphnia magna transcriptomics
Small organisms can be used as biomonitoring tools to assess chemicals in the environment. Chemical stressors are especially hard to assess and monitor when present as complex mixtures. Here, Daphnia magna were exposed for 24 hours to five different munitions constituents 2,4,6-trinitrotoluene (TNT)...
ORGANISM(S): Daphnia magna 
2011-06-22 | E-GEOD-30163 | biostudies-arrayexpress
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