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In plants, exposure to high light irradiation induces various stress responses, which entail complex metabolic rearrangements. To explore these dynamics, we conducted time-course experiments spanning 2 minutes to 72 hours with Arabidopsis thaliana under high and control light. Comparative metabol...

2024-08-16 | MTBLS3109 | MetaboLights
Studying the flow of chemical moieties through the complex set of metabolic reactions that happen in the cell is essential to understanding the alterations in homeostasis that occur in disease. Recently, LC/MS-based untargeted metabolomics and isotopically labeled metabolites have been used to facil...
2015-09-15 | MTBLS213 | MetaboLights
DNA methylation is a key epigenetic modification regulating genome organization, stability, and gene expression. Stable DNA methylation critically relies on methyl groups provided through folate-mediated one-carbon (C1) metabolism, yet the origin and regulation of C1 supply remain elusive. Here we d...
2026-01-06 | MTBLS13444 | MetaboLights

The marine labile dissolved organic carbon (DOC) pool is a dynamic reservoir of thousands of molecules. After excretion or release by phytoplankton and other microbes, metabolites are rapidly consumed, resulting in very low standing concentrations (picomolar to low nanomolar). To date, marine phy...

2026-03-17 | MTBLS12895 | MetaboLights
INTRODUCTION: Rising seawater temperatures are threatening the persistence of coral reefs; where above critical thresholds, thermal stress results in a breakdown of the coral-dinoflagellate symbiosis and the loss of algal symbionts (coral bleaching). As symbiont-derived organic products typically fo...
2018-12-04 | MTBLS538 | MetaboLights
Here, we performed a mass spectrometry-based analysis to study lysine acetylation and proteome dynamics in Chlamydomonas under varying growth conditions. Liquid cultures of Chlamydomonas were transferred from mixotrophic (light and acetate as carbon source) to heterotrophic (dark and acetate), or ph...
ORGANISM(S): Chlamydomonas Reinhardtii 
Analysis of the carbon, photosynthesis etc. pathway under normal and red/blue light conditions in Nannochloropsis oceanica Imet1
ORGANISM(S): Nannochloropsis oceanica strain IMET1 
2021-01-04 | PXD016054 | Pride
The Simple Light Isotope Metabolic labeling (SLIM-labeling) is an inovative method to quantify proteome variations based on an original in vivo labeling strategy. Heterotrophic cells grown on a U-[12C] sole source of carbon synthesize U-[12C]-amino acids which are incorporated into proteins giving r...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-02-15 | PXD021329 | Pride
The Simple Light Isotope Metabolic labeling (SLIM-labeling) is an inovative method to quantify proteome variations based on an original in vivo labeling strategy. Heterotrophic cells grown on a U-[12C] sole source of carbon synthesize U-[12C]-amino acids which are incorporated into proteins giving r...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-02-16 | PXD021502 | Pride
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