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TranscriptomicsTime course analysis of human colorectal cancer liver metastasis models under Sacituzumab Govitecan (SG) treatment or untargeted control
Human colorectal cancer organoids were injected intrasplenically to form liver metastasis in mice were treated with the TROP2-targeting antibody-drug conjugate Sacituzumab Govitecan (SG) or non-targeting control IgG1-SN-38 (ADC). Tumors were harvested at different time points: 0 h, 6 h, 24 h, 48 h,...
ORGANISM(S): Homo sapiens 
2026-04-01 | E-MTAB-16849 | biostudies-arrayexpress
TranscriptomicsYeast carbon and nitrogen impulse transient data in chemostat
Wild type S. cerevisiae cells were grown under glucose or ammonium limitation in fully controlled aerobic chemostat cultures. At steady state, the limited nutrient was introduced into the growth medium in an impulse like manner to recover the medium to its non-limiting conditions. Samples were colle...
ORGANISM(S): Saccharomyces cerevisiae 
2011-10-03 | E-MTAB-643 | biostudies-arrayexpress
TranscriptomicsTime course analysis of human colorectal cancer organoid treatment with Sacituzumab Govitecan (SG) or untargeted control IgG1-SN-38
Human colorectal cancer organoids were treated with the TROP2-targeting antibody-drug conjugate Sacituzumab Govitecan (SG) or non-targeting control IgG1-SN-38. Samples were harvested at different time points under treatment {0h, 3h, 6h, 9h, 12h} as well as after drug washout at 12 h on the following...
ORGANISM(S): Homo sapiens 
2026-04-01 | E-MTAB-16843 | biostudies-arrayexpress
UnknownMonoclonal antibodies targeting the HR2 domain and the region immediately upstream of the HR2 of the S protein neutralize in vitro infection of severe acute respiratory syndrome coronavirus.
Not available
S-EPMC1346840 | biostudies-literature
TranscriptomicsYeast drug resistance gene mutants in glucose or ammonium limited chemostats
Homozygous deletion mutants of drug resistance genes QDR3 and PDR3 and the homozygous deletion of HO (control) were grown in ammonium limited or glucose limited synthetic defined medium in aerated, pH controlled chemostats at a dilution rate of 0.1hr-1. Samples were collected at steady state.
ORGANISM(S): Saccharomyces cerevisiae 
2013-10-23 | E-MTAB-707 | biostudies-arrayexpress
ProteomicsA general multipronged activation approach for natural product discovery in Actinomycetes 54 actinobacterial strains with genetic and cultivation based activation
LC-MS/MS fermentation extract collection of 54 diverse and non-domesticated actinobacterial strains interrogated with a one-step integrase-mediated genetic- and cultivation-based approach to perturb and activate metabolite production in actinobacteria that has significantly increased accessible meta...
ORGANISM(S): Streptomyces Viridochromogenes (ncbitaxon:1938) Streptomyces Abikoensis (ncbitaxon:97398) Thermoactinomyces Vulgaris (ncbitaxon:2026) Streptomyces Albogriseolus (ncbitaxon:1887) Streptomyces Sampsonii (ncbitaxon:42239) Streptomyces Ardesiacus Streptomyces Fradiae (ncbitaxon:1906) Streptomyces Filipinensis (ncbitaxon:66887) Streptomyces Niveiscabiei (ncbitaxon:164115) Streptomyces Odonnellii (ncbitaxon:1417980) Streptomyces Anandii (ncbitaxon:285454) Streptomyces Thermocarboxydus (ncbitaxon:59299) Streptomyces Flaveolus (ncbitaxon:67297) Streptomyces Albofaciens (ncbitaxon:66866) Micromonospora Maris Streptomyces Luridiscabiei (ncbitaxon:164114) Streptomyces Lavendulae (ncbitaxon:1914) Streptomyces (ncbitaxon:1883) Spirillospora Tritici Streptomyces Kronopolitis (ncbitaxon:1612435) Streptomyces Niveoruber (ncbitaxon:68243) Streptomyces Cyaneochromogenes Streptomyces Lunaelactis (ncbitaxon:1535768) Streptomyces Hirsutus (ncbitaxon:35620) Streptomyces Jeddahensis (ncbitaxon:1716141) Streptomyces Tendae Strain Atcc 19812 Micromonospora Oryzae (ncbitaxon:1530046) Streptomyces Nigrescens (ncbitaxon:1920) Streptomyces Durhamensis (ncbitaxon:68194) Streptomyces Variabilis (ncbitaxon:67372) Micromonospora Aurantiaca (ncbitaxon:47850) Streptomyces Tendae (ncbitaxon:1932) Micromonospora Maritima (ncbitaxon:986711) Streptomyces Globisporus (ncbitaxon:1908) Dactylosporangium Solaniradicis (ncbitaxon:1758122) 
2023-06-22 | MSV000092237 | MassIVE
UnknownThe use of hepatitis C virus NS3/4A and secreted alkaline phosphatase to quantitate cell-cell membrane fusion mediated by severe acute respiratory syndrome coronavirus S protein and the receptor angiotensin-converting enzyme 2.
Not available
S-EPMC7094373 | biostudies-literature
UnknownAssociation Between Subjective-Objective Discrepancy of Sleeping Time and Health-Related Quality of Life: A Community-Based Polysomnographic Study.
Not available
S-EPMC9064942 | biostudies-literature
UnknownSKI-G-801, an AXL kinase inhibitor, blocks metastasis through inducing anti-tumor immune responses and potentiates anti-PD-1 therapy in mouse cancer models.
Not available
S-EPMC8716998 | biostudies-literature
MetabolomicsThe downside of metabolic diversity: Postingestive rearrangements by specialized insects
Deploying toxins in complex mixtures is thought to be advantageous and is observed during antagonistic interactions in nature. Toxin mixtures are widely utilized in medicine and pest control, as they are thought to slow the evolution of detoxification counterresponses in the targeted organisms. Here...
2022-12-04 | MTBLS3676 | MetaboLights
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