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ProteomicsRb and the APC/C coactivator FZR1 determine CDK4/6-Cyclin D requirement in C. elegans and human cancer cells
Cyclin dependent kinase 4 and 6 (CDK4/6) in complex with D-type cyclins promote cell cycle entry, at least in part through phosphorylation of the retinoblastoma tumor suppressor protein (Rb). The CDK4/6-cyclin D-Rb pathway is commonly deregulated in human cancer, often through CDK4/6 or D-type cycli...
ORGANISM(S): Homo sapiens (Human) Caenorhabditis elegans 
2016-07-05 | PXD001501 | Pride
Lin-35 fzr1 
TranscriptomicsHepatic transcriptome of mice fed high fat diets containing palm or linseed oil
The beneficial effects of dietary long-chain (LC) n-3 polyunsaturated fatty acids (PUFA) in the prevention and/or treatment of some metabolic disorders result largely from their capacity to regulate the transcription level of many genes involved in metabolic and physiological homeostasis, especially...
ORGANISM(S): Mus musculus 
2016-05-18 | E-GEOD-73290 | biostudies-arrayexpress
UnknownStromal C-type lectin receptor COLEC12 integrates H. pylori, PGE2-EP2/4 axis and innate immunity in gastric diseases.
Not available
S-EPMC5830506 | biostudies-literature
TranscriptomicsGene expression profiling of novel antigen presenting cells (APC) inducing pathogenic T helper cells of lupus
In lupus autoimmunity, pathogenic IgG autoantibodies that fix complement and bind FcGammaR on inflammatory cells, are produced with help from T helper (Th1 and Th17) cells specific for peptides from nucleosomes of apoptotic cells; and these Th cells also infiltrate vital organs (1-9). Macrophages (...
ORGANISM(S): Mus musculus 
2012-06-20 | E-GEOD-36284 | biostudies-arrayexpress
Unknown8,14-Secogammacera-7,14(27)-diene-3,21-dione-8,14-secogammacera-7,14-diene-3,21-dione (1.5/0.5) from the bark of Lansium domesticum Corr.
Not available
S-EPMC2969586 | biostudies-literature
TranscriptomicsExpression data from P15 mouse testes control and Ikbkap-knockout mice
Ikbkap/Elp1 regulates genes involved in spermatogenesis. Ikbkap deficiency causes male infertility by disrupting meiotic progression. In this dataset, we include the expression data for control and Ikbkap-knockout mouse testis. We analyzed the gene expression in control and Ikbkap-knockout testes us...
ORGANISM(S): Mus musculus 
2013-12-31 | E-GEOD-42230 | biostudies-arrayexpress
Unknown(Benzophenone imine-κN)-chlorido(hydrido-tripyrazolyl-borato)-(triphenyl-phosphine)ruthenium(II) diethyl ether solvate.
Not available
S-EPMC2959639 | biostudies-literature
UnknownBis(μ-9-anthracenemethano-lato)bis-[dimethyl-aluminium(III)].
Not available
S-EPMC2971356 | biostudies-literature
Unknown(O,O'-Diethyl dithio-phosphato-κS,S')(hydridotripyrazol-1-ylborato-κN,N,N)(triphenyl-phosphine-κP)ruthenium(II).
Not available
S-EPMC2959604 | biostudies-literature
UnknownAdverse respiratory events with sevoflurane compared with desflurane in ambulatory surgery: A systematic review and meta-analysis.
Not available
S-EPMC7752224 | biostudies-literature
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